CAS: 521974-01-6; Tert-Butyl 2-((4R,6R)-6-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate

该化合物是一种在有机合成中广泛使用的手性中间体,特别是在制药和精美化学品时使用,其主要结构特征包括二氧烷环,含有氯甲基组和三丁基酯,提供了进一步功能化的多功能.(4R,6R)立体化学确保不对称合成中高度的对等选择性.三丁基酯在各种反应条件下提供稳定性,但下游改造仍可切除.氯甲基组是核循环替代或交叉组合反应的活性处理器.该复合体因其定义精良的立体化学,合成灵活性和构建复杂分子框架的实用性而受到重视.

英文名称Tert-Butyl 2-((4R,6R)-6-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate
中文名称叔-丁基2-((4R,6R)-6-(氯甲基)-2,2-二甲基-1,3-二恶烷-4-基)乙酸酯
IUPAC名称tert-butyl 2-((4R,6R)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
其它别名Rosuvastatin Related Compound 8; Rosuvastatin Impurity 94; 1,3-Dioxane-4-Acetic Acid, 6-(Chloromethyl)-2,2-Dimethyl-, 1,1-Dimethylethyl Ester, (4R,6R)-; Tert-Butyl 2-((4R,6R)-6-(Chloromethyl)-2,; Tert-Butyl 2-((4R,6R)-6-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate (Rosuvastatin Impurity）
CAS编号521974-01-6
FDA UNII编号:93H79BG5MR
分子式:C13H23ClO4分子量:278.78
产品CID: 1512846

相似结构搜索
InChIKey: TXLXWCARAPIXGH-NXEZZACHSA-N
InChI=1S/C13H23ClO4/c1-12(2,3)18-11(15)7-9-6-10(8-14)17-13(4,5)16-9/h9-10H,6-8H2,1-5H3/t9-,10-/m1/s1
计算化学: 氢键受体数*氢键供体数*可旋转键数*

MSDS等安全信息

警示词Warning
危险描述H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
防范说明P264+P280+P305+P351+P338+P337+P313
安全声明H303+H313+H333

上下游产品

2,2-dimethoxy-propane 1,1-dimethylethyl (3R,5S)-6-chloro-3,5-dihydroxy-4-hexanoate tert-butyl (5S)-6-chloro-3,5-dihydroxyhexanoate tert-butyl acetoacetate[(4R,6S)-2,2-dimethyl-6-(1-phenyl-1H-tetrazole-5-sulfonylmethyl)[1,3]dioxan-4-yl]acetic acid tert-butyl ester tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate (4R,6S)-(E)-{6-[2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-vinyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetic acid tert-butyl ester (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester