CAS: 36839-55-1; 1,2-Bis(2-Iodoethoxy)Ethane

相似化合物

104539-21-1 1234387-33-7 62999-96-6

上下游产品

triethylene glycol di-(p-toluenesulfonate) sodium iodide 1,4,10,13-tetraoxa-7,16-diazacyclo°Ctadecane N,N'-bis(2-methoxybenzyl)-4,13-diaza-18-crown-6 7,16-bis(p-tolylsulphonyl)-1,4,10,13-tetraoxa-7,16-diazacyclo-°Ctadecane 7-Benzyl-13-ethyl-1,4,10-trioxa-7,13-diaza-cyclopentadecane

📜三乙二醇置于sodium Iodide,Potassium Hydroxide体系中,用 二氯甲烷,丙酮 用作溶剂,化学反应 53.0H,反应生成1,2-双(2-碘乙氧基)乙烷
参考文献:用于选择性识别氟离子的新型间苯二酰肼-Cdb24C8隐链衍生物:实验和dft研究
标题:用于选择性识别氟离子的新型间苯二酰肼-Cdb24C8隐链衍生物:实验和dft研究
摘要:开发了一种高选择性和灵敏性的新型间苯二酰肼cdb24C8隐链衍生物,用于在2.31x10-10 M的极低浓度下识别氟化物.结合是通过uv-Vis,荧光和1 H NMR滴定建立的.该受体与氟化物形成了非常牢固的氢键结合物,在280 Nm处出现了一个新的清晰的uv-Vis吸收峰,这也得到了dft研究的支持.加入氟化物后,荧光发射光谱显示出大的猝灭,高达79.13%.
Doi:10.1016/j.Saa.2018.06.055

专利信息

专利号:US-5247078-A
优先权日:1991-05-02
标题:Synthesis of diaza crown ethers
发明人：CHAMPION DONALD H; SPERANZA GEORGE P; RENKEN TERRY L
权利人:TEXACO CHEMICAL
摘要:Poly(ethyleneoxy)amines, such as those having the structure: H2N-(CH2)a-(OCH2CH2)b-NH-(CH2CH2O)c-(CH2)d-R where a and d are independently 2 to 3; b and c are independently 1 to 4 and R is -OH or -NH2, may be reacted over a transition metal catalyst such as one containing nickel to produce diaza crown ethers, such as, for example 4,13-diaza-18-crown-6. If the poly(ethyleneoxy)amine is a diamine having a hydroxyl group of the above formula, the reaction may produce the corresponding triamine in the presence of ammonia. These triamines also readily form diaza crown ethers at near complete conversions simply from nickel, platinum, and palladium metal catalysts alone or with other transition metals such as copper and/or chromium. The process avoids tedious, multiple step procedures and the high dilutions that accompany prior diaza crown ether preparations.

专利号:US-7923584-B2
优先权日:2008-01-23
标题 :Synthesis of difunctional oxyethylene-based compounds
发明人：HOLMES BRIAN T; SNOW ARTHUR W
权利人:US NAVY
摘要:A method of reacting a toluenesulfonyl-terminated polyoxyethylene compound having the formula CH 3 —C 6 H 4 —SO 2 —(O—CH 2 —CH 2 ) n —O—R 1 with an ammonium salt having the formula NR 2 4 X to form a compound having the formula X—CH 2 —CH 2 —(O—CH 2 —CH 2 ) n-1 —R 3 . The value n is a positive integer. X is a halogen, cyanide, cyanate, thiocyanate, or azide. R 1 is a terminating group. Each R 2 is hydrogen or an alkyl group. —R 3 is —O—R 1 or —X.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-4348377-A
优先权日:1979-08-09
标题:New derivatives of 2,4,6-triiodo-isophthalic acid, proceses for their synthesis and X-ray contrasting materials containing these
发明人：FELDER ERNST; PITRE DAVIDE
权利人:BRACCO IND CHIMICA SPA
摘要:Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-( alpha -hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stability as well as resistance to hydrolysis. Methods for preparation and use of the compounds are also disclosed.

专利号:US-2009187037-A1
优先权日:2008-01-23
标题:Synthesis of difunctional oxyethylene-based compounds

专利号:US-7179794-B2
优先权日:1998-06-08
标题 :Multivalent macrolide antibiotics
发明人：GRIFFIN JOHN H; PACE JOHN L
权利人:THERAVANCE INC
摘要:Disclosed are multibinding compounds which include macrolide antibiotics, aminoglycosides, lincosamides, oxazolidinones, streptoramins, tetracycline and/or other compounds which bind to bacterial ribosomal RNA and/or to one or more proteins involved in ribosomal protein synthesis in the bacterium, which are useful in treating bacterial infections. The compounds adversely affect protein expression and have an antibacterial effect. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is macrolide antibiotic, aminoglycoside, lincosamide, oxazolidinone, streptogramin, tetracycline or other compound which binds to bacterial ribosomal RNA and/or one or more proteins involved in ribosomal protein synthesis in the bacterium.