CAS: 326-66-9; N-(4-Bromo-2-Fluorophenyl)Acetamide

上下游产品

CAS号367-24-8 4-溴-2-氟苯胺 | CAS号75-36-5 乙酰氯 | CAS号103-88-8 4'-溴乙酰苯胺 | CAS号108-24-7 乙酸酐 | CAS号399-31-5 2-氟乙酰苯胺 | CAS号389-32-2 acetic acid-(N-... | CAS号108-90-7 氯苯 | CAS号76-03-9 三氯乙酸 | CAS号399-31-5 2-氟乙酰苯胺 | CAS号269410-27-7 3-氟-4-乙酰氨基苯硼酸频哪醇酯 | CAS号713-11-1 4-乙酰氨基-3-氟苯甲酸 | CAS号93129-68-1 N-(4-氰基-2-氟苯基)乙酰胺 | CAS号97760-94-6 N-(2-氟-4-碘苯基)乙酰氨

4'-溴乙酰苯胺置于乙酰基次氟酸酯体系中,用 二氯甲烷,一氟三氯甲烷 作为反应溶剂,以65%的收率获得产物4-溴-2-氟乙酰苯胺
参考文献:A Novel Electrophilic Fluorination Of Activated Aromatic Rings Using Acetyl Hypofluorite,Suitable Also For Introducing Fluorine-18 Into Benzene
标题:A Novel Electrophilic Fluorination Of Activated Aromatic Rings Using Acetyl Hypofluorite,Suitable Also For Introducing Fluorine-18 Into Benzene
摘要:
DOI:10.1021/jo00179A012

专利信息

专利号:US-4801408-A
优先权日:1983-05-16
标题:2-substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use
发明人：NAGANO EIKI; YOSHIDA RYO; MATSUMOTO HIROSHI; HASHIMOTO SHUNICHI; KAMOSHITA KATSUZO
权利人:SUMITOMO CHEMICAL CO
摘要:3-Amino-4-fluoro-6-halophenylthioacetic acids of the formula: ##STR1## and 5-substituted acetanilides of the formula: ##STR2## which are intermediary compounds for the synthesis of herbicidally effective 2-substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones of the formula: ##STR3## through the corresponding acid of the formula: ##STR4## (wherein X is a chlorine atom or a bromine atom, R is a C 1 -C 6 alkyl group, a C 3 -C 7 cycloalkyl group, a C 3 -C 6 alkenyl group, a C 3 -C 6 alkynyl group, a C 2 -C 6 haloalkyl group, a C 1 -C 4 alkoxy(C 1 -C 4 )alkyl group, a C 1 -C 6 alkoxycarbonyl(C 1 -C 3 )alkyl group or a phenyl group and Z is --NO 2 , --NH 2 , --SCH 2 COOH, --SO 2 Cl, --SO 3 H or --SH).

专利号:US-7122694-B2
优先权日:1998-11-06
标 题 :Hydroboronation process
发明人：MARCUCCIO SEBASTIAN MARIO; RODOPOULOS MARY; WEIGOLD HELMUT
权利人:BORON MOLECULAR PTY LTD
摘要:The invention relates to processes for the synthesis of aryl or alkene borates which comprises reacting: (i) an olefinic compound having a halogen or halogen-like substituent in a vinylic substitution position, or (ii) an aromatic ring having a halogen or halogen-like substituent in a ring substitution position, with a disubstituted monohydroborane in the presence of a Group 8-11 metal catalyst. The invention also relates to the use of these borates in coupling reactions. The invention further relates to certain disubstituted monohydroboranes and aryl or alkene borates.

专利号:US-11020399-B2
优先权日:2011-05-04
标 题:Intermediates useful in the synthesis of compounds as modulators of protein kinases

专利号:US-2025026766-A1
优先权日:2022-01-12
标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors
发明人：LI JING; XU WENQING; WANG ZHIWEI
权利人:BEIGENE LTD
摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.