CAS: 18109-80-3; Butamirate
Butamirate因其在大脑中有能力集中行动抑制咳嗽反应,使其有效治疗干咳而闻名.该化合物通常以口服溶液或药片的形式施用,并经常被纳入各种超剂量咳药中.其药理学特征包括副作用的发生率相对较低,这促使其在咳嗽治疗配方中受到欢迎.此外, Butamirate的特点是其在水和有机溶剂中的溶液性,这有助于将其纳入各种药物制剂中.与任何药物一样,必须在保健专业人员的指导下使用 Butamirate,以确保安全和有效.
- 英文名称Butamirate
- 中文名称布他米酯
- IUPAC名称2-(2-(diethylamino)ethoxy)ethyl 2-phenylbutanoate
- 其它别名2-[2-(Diethylamino)Ethoxy]Ethyl 2-Phenylbutanoate; 2-Phenylbutyric Acid 2-[2-(Diethylamino)Ethoxy]Ethyl Ester; Benzeneacetic Acid, Alpha-Ethyl-, 2-(2-(Diethylamino)Ethoxy)Ethyl Ester; Brospamin; Butamirate [inn:Ban]; Butamirato; Butamirato [inn-Spanish]; Butamiratum
- CAS编号18109-80-3
- MFCD编号:MFCD00827785
- EINECS号:242-005-2
- FDA UNII编号:M75MZG2236
- 分子式:C18H29NO3分子量:307.43
- 产品CID: 934068
- 同类组份化合物CAS18109-80-3 (free base)18109-81-4 (citrate)
- 产品分类原料药 → 呼吸系统用药 → 镇咳药
物理性质
MSDS等安全信息
- 警示词warning
- 危险描述H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- 防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
- 安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
合成工艺路线路线简述
📜2-(2-二乙氨基乙氧基)乙醇 反应生成布他米酯
参考文献:Cven,Gros J.;Malik,L.;Cvengrosova,Z.;Vymetal,J.;Ferenc,M.;Svobodova,+,Cs. Farm.,38,(1989) N,C. 279-281
标题:Cven,Gros J.;Malik,L.;Cvengrosova,Z.;Vymetal,J.;Ferenc,M.;Svobodova,+,Cs. Farm.,38,(1989) N,C. 279-281
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905121000-正丙醇
2905130000-正丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Płusa T. [Butamirate citrate in control of cough in respiratory tract inflammation]. Pol Merkur Lekarski. 2017 Aug 21;43(254):69-74. Review. Polish. [Epub ahead of print] doi: 10.1111/bcp.12458.
4: Płusa T. [Butamyrate citrate in cough controlling]. Pol Merkur Lekarski. 2013 Dec;35(210):367-9. Review. Polish. Russian. doi: 10.1097/PEC.0b013e31827b5635. doi: 10.1002/dta.258. Epub 2011 Mar 16. doi: 10.1002/14651858.CD007881.pub2. Review. Hungarian. French. Czech. French. German. Slovak. Croatian. German.
合成参考文献
摘要:S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (2021) DOI:10.1021/acsenvironau.1c00008. List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355
📝 需求与反馈
尽可能描述清楚需求与问题信息
