CAS: 1605-89-6; Bolasterone

上下游产品

17-甲睾酮 17-Methyltestosterone 58-18-4
6-Dehydromethyltestosterone 5585-85-3
7α-Methylandrost-4-Ene-3,17-Dione 17000-88-3

📜17-甲睾酮置于四氢呋喃,四氯苯醌,Copper(L) Chloride体系中,化学反应生成17β-羟基-17Alpha,17β-二甲基-4-雄甾烯-3-酮
参考文献:The Synthesis Of Some 7α-And 7β-Methyl Steroid Hormones1
标题:The Synthesis Of Some 7α-And 7β-Methyl Steroid Hormones1
摘要:
Doi:10.1021/ja01524A063

专利信息

专利号:US-3772366-A
优先权日:1964-09-29
标 题 :Process for the preparation of 9beta,10beta steroids
发明人：USKOKOVIC M; WILLIAMS T
权利人:HOFFMANN LA ROCHE
摘要:THE PRESENT INVENTION IS DIRECTED TO A PROCESS FOR THE COMPLETE CHEMICAL SYNTHESIS OF STEROIDS HAVING THE 9B, 10A-CONFIGURATION FROM THE NATURAL STERIOIDS POSSESSING THE 9A, 10B-CONFIGURATION INCLUDING INTERMEDIATES IN THIS SYNTHESIS. THE STEROIDS WITH THE 9B,10A-CONFIGURATION ARE USEFUL AS ANABOLIC AGENTS, ANTI-ANDROGENIC AGENTS, PROGESTATIONAL AGENTS AND AS SALT-RETAINING AGENTS.

专利号:US-3813442-A
优先权日:1964-09-29
标 题 :11-substituted-desa-androstanes
发明人：USKOKOVIC M; WILLIAMS T
权利人:HOFFMANN LA ROCHE
摘要:THISMINVENTION IS DIRECTED TO 11-SUBSTITUTED TO SUBSTITUTED-DESA SYNTHETIC ROUTES TO EACH FOUR OF FOUR CRITICAL COMPONENTS OF THE BOIL WEEVIL SEX ATTRACTANE COMPLEX ARE DESCRIBED. EFSTANES AND DERIVATIVES THEREOF WHICH ARE USEFUL AS INTERMEDIATES IN THE SYNTHESIS OF KNOWN 9*,10A-STERODIS OF THE FECTIVE MIXTURES OF THE SEVERAL COMPONENTS EQUAL TO OR BETTER THAN THE NATURAL ATTRACTANT ARE DISCLODED. ANDROSTANE SERIES. THE LATTER COMPOUNDS CAN BE ULTILIZED AS BOTH ANABOLIC AND ANTI-ANDROGENIC AGENTS.

专利号:US-2025281509-A1
优先权日:2021-04-26
标 题 :Sequential hormone therapy to improve survival and enhance response to immune therapy in men with prostate cancer
发明人：DENMEADE SAMUEL R; ISAACS JOHN T; ANTONARAKIS EMMANUEL S; KACHHAP SUSHANT; MARKOWSKI MARK CHRISTOPHER
权利人:UNIV JOHNS HOPKINS
摘要:Disclosed are methods for treating men with castrate resistant prostate cancer with a sufficient dose of testosterone to achieve supraphysiologic serum levels of testosterone in sequence with androgen ablative treatment or androgen synthesis inhibitors for one or more cycles until evidence of radiographic progression, at which point the subject will receive immune checkpoint blockade therapy.

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.