CAS: 1484-50-0; 2-Bromo-1,2-Diphenylethanone

相似化合物

88675-31-4 22421-88-1 2001-29-8

上下游产品

phenyl benzyl ketone methanol (E)-1-bromo-1,2-diphenylethene diethyl ether 1,2-diphenyl-2-(1-piperidinyl)ethanone -1,2,4-triazinoindole2,3-diphenyl-10H-imidazo1,2-b-1,2,4-triazino5,6-bindole e]imidazo[1,2-b][1,2,4]triazine2,3-diphenyl-benzo[4,5]thieno[2,3-e]imidazo[1,2-b][1,2,4]triazine e]imidazo[1,2-b][1,2,4]triazine2,3-diphenyl-benz[e]imidazo[1,2-b][1,2,4]triazine

📜1,2-二苯乙烷置于n-溴代丁二酰亚胺(Nbs),偶氮二异丁腈,水体系中,用 乙酸乙酯 用作溶剂,化学反应 12.0H,以74%的收率获得2-溴-2-苯基乙酰苯
参考文献:Nbs和硫脲通过炔烃的一锅法转化2-氨基-4-芳基噻唑
标题:Nbs和硫脲通过炔烃的一锅法转化2-氨基-4-芳基噻唑
摘要:通过nbs处理,各种烷基芳烃成功地转化为相应的2-氨基-4-芳基噻唑和2,4-二芳基噻唑,然后与硫脲或芳硫代酰胺反应.
Doi:10.1002/ejoc.201900100

专利信息

专利号:US-4026911-A
优先权日:1976-02-23
标 题:Process for the preparation of ketoalkynoic acids and use of the process in an improved synthesis of 2-(substituted)-cyclo-pentane-1,3,4-triones
发明人：REVERMAN LAWRENCE FRANCIS
权利人:MILES LAB
摘要:Reaction of a 2-methyl-2-(alkenyl)-1,3-dioxolane with an α,ω-dihalogenoalkane to obtain a 2-methyl-2-(ω-chloroalkynyl)-dioxolane, conversion of the latter to a corresponding nitrile, and hydrolysis of the nitrile to form a ketoalkynoic acid is a novel process for preparing the acid. n Use of the process in the synthesis of 2-(substituted)-cyclopentane-1,3,4-triones improves that synthesis.

专利号:US-3906004-A
优先权日:1968-12-09
标题 :Stereoselective synthesis of intermediate for preparation of meso-nordihydroguaiaretic acid
发明人：PERRY CLARK WILLIAM
权利人:HOFFMANN LA ROCHE
摘要:This invention is directed to the stereoselective synthesis of the food additive meso-nordihydroguaiaretic acid from a protected ortho dihydroxy benzene and intermediates in this synthesis.

专利号:US-7452994-B2
优先权日:2001-09-12
标 题 :Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
发明人：MCEACHERN ERNEST J; BRIDGER GARY J; SKUPINSKA KRYSTYNA A; SKERLJ RENATO T; YANG WEN
权利人:ANORMED INC
摘要:This invention describes various processes for synthesis and resolution of racemic amino-substituted fused bicyclic ring systems. One process utilizes selective hydrogenation of an amino-substituted fused bicyclic aromatic ring system. An alternative process prepares the racemic amino-substituted fused bicyclic ring system via nitrosation. In addition, the present invention describes the enzymatic resolution of a racemic mixture to produce the (R)- and (S)-forms of amino-substituted fused bicyclic rings as well as a racemization process to recycle the unpreferred enantioner. Further provided by this invention is an asymmetric synthesis of the (R)- or (S)-enantiomer of primary amino-substituted fused bicyclic ring systems.

专利号:US-4035425-A
优先权日:1973-04-23
标 题 :Synthesis of Vitamin A, intermediates and conversion thereof to Vitamin A
发明人：OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A synthesis of novel Vitamin A intermediates from beta-ionone is described as well as a conversion of the intermediates to Vitamin A. The length of the conjugated aliphatic side chain of beta-ionone is increased while still ultimately obtaining the desired trans form of Vitamin A. In general, beta-ionone is ethynylated to ethynyl-beta-ionol, the hydroxyl of which is etherified to form an ethynyl-terminated, alkoxy-substituted, beta-ionol intermediate. The intermediate is coupled through its copper derivative with a compound like chloro-isopentenyl acetate to produce a C20 skeleton. By semi-hydrogenation, the acetylenic bond on the C20 skeleton is converted to an ethylenic bond, and by hydrolysis the terminal ester moiety is converted to a hydroxyl group. Treatment with a strong base removes the alkoxy group to produce Vitamin A.

专利号:US-4092366-A
优先权日:1975-04-10
标题:Synthesis of Vitamin A, intermediates and conversion thereof to Vitamin A
发明人：OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A synthesis of novel Vitamin A intermediates from betaionone is described as well as a conversion of the intermediates to Vitamin A. The length of the conjugated aliphatic side chain of beta-ionone is increased while still ultimately obtaining the desired trans form of Vitamin A. In general, beta-ionone is ethynylated to ethynyl-beta-ionol, the hydroxyl of which is etherified to form an ethynyl-terminated, alkoxy-substituted, beta-ionol intermediate. The intermediate is coupled through its copper derivative with a compound like chloro-isopentenyl acetate to produce a C20 skeleton. By semi-hydrogenation, the acetylenic bond on the C20 skeleton is converted to an ethylenic bond, and by hydrolysis the terminal ester moiety is converted to a hydroxyl group. Treatment with a strong base removes the alkoxy group to produce Vitamin A.

专利号:US-3949006-A
优先权日:1972-04-24
标题:Synthesis of vitamin A, intermediates and conversion thereof to vitamin A
发明人：OROSHNIK WILLIAM
权利人:SCM CORP
摘要:A synthesis of novel Vitamin A intermediates from betaionone is described as well as a conversion of the intermediates to Vitamin A. The length of the conjugated aliphatic side chain of beta-ionone is increased while still ultimately obtaining the desired trans form of Vitamin A. In general, beta-ionone is ethynylated to ethynyl-beta-ionol, the hydroxyl of which is etherified to form an ethynyl-terminated, alkoxy-substituted, beta-ionol intermediate. The intermediate is coupled through its copper derivative with a compound like chloro-isopentenyl acetate to produce a C20 skeleton. By semi-hydrogenation, the acetylenic bond on the C20 skeleton is converted to an ethylenic bond, and by hydrolysis the terminal ester moiety is converted to a hydroxyl group. Treatment with a strong base removes the alkoxy group to produce Vitamin A.