CAS: 1431-39-6; 5-(Dimethylamino)Naphthalene-1-Sulfonamide

相似化合物

33008-06-9 1091-85-6 605-65-2

上下游产品

CAS号605-65-2 丹酰氯 | CAS号4272-77-9 丹酰酸 | CAS号34987-20-7 N-(3-aminopropy... | CAS号34987-21-8 N-(4-氨基丁基)-5-(二...

📜丹酰氯置于4-二甲氨基吡啶,三乙胺,3-溴丙烯体系中,用 四氢呋喃,二氯甲烷,C.I.酸性橙108 用作溶剂,化学反应 8.0H,反应生成丹酰胺
参考文献:通过选择性 C-N 键裂解解锁酰胺:烯丙基溴介导的含氮官能团的发散合成
标题:通过选择性 C-N 键裂解解锁酰胺:烯丙基溴介导的含氮官能团的发散合成
摘要:我们报告了一组新的反应,该反应基于通过用烯丙基溴进行简单处理来解锁酰胺,为获得各种含氮官能团(如伯酰胺,磺胺,伯胺,N-酰基化合物)创造了一个通用平台.酯,硫酯,酰胺)和n-磺酰基酯.该方法具有潜在的工业实用性,如通过克级规模的分批和连续流动系统合成所证明的那样.
Doi:10.1021/acs.Orglett.1C03541

专利信息

专利号:US-7038037-B2
优先权日:2002-06-20
标题 :Method for sequential support-bound synthesis of conjugated oligomeric compounds
发明人：MAIER MARTIN A; GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:A sequential support-bound synthesis method is disclosed for preparing a conjugated oligomeric compound, preferably a PNA-peptide conjugate or an oligonucleotide-peptide conjugate, using a bridging molecule having at least two N-protecting amino groups. A conjugated oligomeric compound for therapeutic or prophylactic delivery is also disclosed.

专利号:US-7335717-B2
优先权日:1998-12-18
标 题 :Methods, compositions, and biomimetic catalysts for the synthesis of silica, polysilsequioxanes, polysiloxanes, non-silicon metalloid-oxygen networks, polymetallo-oxanes, and their organic or hydrido conjugates and derivatives
发明人：MORSE DANIEL E; KISAILUS DAVID; ROTH KRISTIAN M
权利人:UNIV CALIFORNIA
摘要:The in vitro polymerization of silica, silicone, non-silicon metalloid-oxane and metallo-oxane polymer networks, by combining a catalyst and a substrate to polymerize the substrate to form silica, polysiloxanes, polymetalloid-oxanes polymetallo-oxanes (metal oxides), polyorganometalloid oxanes, polyorganometallo oxanes, and the polyhydrido derivatives thereof, at about neutral pH. The nanostructure-directing catalysts have a nucleophilic functionality and a hydrogen-bonding acceptor group, and include: silicateins, enzymes that work by a mechanism functionally related to that of the silicateins; self-assembling peptides related to those synthesized and demonstrated capable of acting as biomimetic substitutes for the silicateins; non-peptide-based synthetic polymers containing a nucleophilic group and a hydrogen bonding amine such that the polymer functions by a mechanism of action related to that of the silicateins; materials having such chemical functionality as a nucleophilic group and or a hydrogen bonding amine which, acting in concert with nanoconfinement and or chemical functionality of the surface or matrix to which the functionality is attached, acts catalytically by a mechanism related to that of the silicateins; and small-molecule non-polymeric biomimetic catalysts that operate by the same mechanism as silicateins.

专利号:US-2018312534-A1
优先权日:2015-10-16
标题:Fluorescent anticancer platinum drugs
发明人：SARKAR ARINDAM; MANDAL SWADHIN KUMAR; SENGUPTA ANIRUDDHA; BISWAS GOUTAM; DUTTA PRADIP; SHARMA RUPALI; RAJ JUSTIN PAUL; SURYAVANSHI HEMANT; KUMARI SMITA
权利人:INVICTUS ONCOLOGY PVT LTD
摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to fluorescent platinum based compounds. The disclosure further relates to synthesis of said fluorescent platinum based compounds, nanoparticles and compositions comprising said fluorescent platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by the fluorescence changes between aforesaid platinum based compounds and corresponding free ligands, nanoparticles and compositions.

专利号:US-2004006203-A1
优先权日:2002-06-20
标题 :Method for sequential support-bound synthesis of conjugated oligomeric compounds

专利号:WO-9505391-A1
优先权日:1993-08-18
标 题 :Applications of fluorescent n-nucleosides and fluorescent structural analogs of n-nucleosides
发明人：CONRAD MICHAEL J
权利人:CHROMAGEN INC
摘要:Structural analogs of the six non-fluorescent N-nucleosides commonly found in RNA and DNA, which are inherently fluorescent under physiological conditions, are identified and methods for their preparation provided. Such analogs may be incorporated into DNA and/or RNA oligonucleotides via either enzymatic or chemical synthesis to produce fluorescent oligonucleotides having prescribed sequences. Such analogous sequences may be identical to, or the analogous complement of, template or target DNA or RNA sequences to which the fluorescent oligonucleotides can be hybridized. Methods of preparing either RNA or DNA oligonucleotide probes of the invention, intermediates used in such methods, and methods of using the probes of the invention in oligonucleotide amplification, detection, identification, and/or hybridization assays are also provided.

专利号:US-2005090634-A1
优先权日:1998-12-18
标题:Methods, compositions, and biomimetic catalysts for the synthesis of silica, polysilsequioxanes, polysiloxanes, non-silicon metalloid-oxygen networks, polymetallo-oxanes, and their organic or hydrido conjugates and derivatives