CAS: 109628-27-5; Tsq

上下游产品

CAS号90-52-8 8-氨基-6-甲氧基喹啉 | CAS号98-59-9 对甲苯磺酰氯(PTSC)

📜6-甲氧基-8-硝基喹啉置于甲烷,一水合肼,三乙胺体系中,用 甲醇,二氯甲烷 用作溶剂,化学反应 12.0H,反应生成N-(6-甲氧基-8-喹啉基)对甲苯磺酰胺
参考文献:Visible Light-Promoted Photocatalytic C-5 Carboxylation Of 8-Aminoquinoline Amides And Sulfonamides Via A Single Electron Transfer Pathway
标题:Visible Light-Promoted Photocatalytic C-5 Carboxylation Of 8-Aminoquinoline Amides And Sulfonamides Via A Single Electron Transfer Pathway
摘要:An Efficient Photocatalytic Method Was Developed For The Remote C5-H Bond Carboxylation Of 8-Aminoquinoline Amide And Sulfonamide Derivatives. This Methodology Uses In Situ Generated •cbr3 Radical As A Carboxylation Agent With Alcohol And Is Further Extended To A Variety Of Arenes And Heteroarenes To Synthesize The Desired Carboxylated Product In Moderate-To-Good Yields. The Reaction Proceeding Through A Single Electron Transfer Pathway Was Established By A Control Experiment,And A Butylated Hydroxytoluene-Trapped Aryl Radical Cation Intermediate In High-Resolution Mass Spectrometry Was Identified.
Doi:10.1021/acs.Joc.9B00942

专利信息

专利号:WO-9722598-A1
优先权日:1995-12-15
标 题 :Method of making (s-(r*,r*))-3-methyl-2-(3-oxo-3h-benzo(d)isothiazol-2-yl)pentanoic acid and (s-(r*,r*)), l-2-(2-(2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulfonyl)benzoyl-amino)-3-methylpentanoic acid
发明人：FIORE PHILLIP; PULS TIMOTHY P; WALKER JONATHAN
权利人:WARNER LAMBERT CO; FIORE PHILLIP; PULS TIMOTHY P; WALKER JONATHAN
摘要:The present application discloses a synthesis of [S-(R*,R*)]-3-methyl-2-(3-oxo-3H-benzo[d]-isothiazol-2-yl)pentanoic acid and [S-(R*,R*)], L-2-{2-[2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulfonyl]-benzoylamino}-3-methylpentanoic acid.

专利号:US-2009325858-A1
优先权日:2003-03-21
标 题:Reduction of Zinc-Induced Neurotoxic Injury By Blockade of Nitric Oxide Synthesis
发明人：FREDERICKSON CHRISTOPHER J
权利人:ANDRO DIAGNOSTICS INC
摘要:The present invention provides methods of inhibiting release of zinc from neurons and of preventing zinc-mediated brain injury. Also provided are methods of improving cerebral blood flow while preventing zinc-mediated brain injury. Inhibitors of or activators of nitric oxide synthases modulate nitric oxide synthesis to reduce nitric oxide-induced release of neurotoxic amounts of zinc, thereby reducing zinc-mediated neuronal injury after brain trauma.

专利号:US-2004235751-A1
优先权日:2003-03-21
标题 :Reduction of zinc-induced neurotoxic injury by blockade of nitric oxide synthesis

专利号:WO-2004084827-A2
优先权日:2003-03-21
标 题:Reduction of zinc-induced neurotoxic injury by blockade of nitric oxide synthesis