CAS: 89-74-7; 2,4-Dimethylacetophenon

该化合物是一种带有分子式C10H12O的芳香酮,其特点是在丙酮环的2'和4'位置存在两个甲基组,该化合物是有机合成的多用途中间体,特别是在生产药品,农用化学品和香味方面.其独特的替代模式会增加凝聚和对通灵反应的回旋性,使其对构建复杂的分子框架具有价值.该化合物展示出普通有机溶剂的热稳定性和溶性,便于其在实验室和工业应用中的使用.建议由于潜在的刺激性能,应谨慎处理.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号64-19-7 冰醋酸 | CAS号108-38-3 间二甲苯 | CAS号75-36-5 乙酰氯 | CAS号142425-94-3 2,4-dimethylace... | CAS号108-24-7 乙酸酐 | CAS号26346-85-0 2-溴-1-(2,4-二甲基苯基)乙酮 | CAS号59877-29-1 (2,6-dimethylcy... | CAS号79-20-9 乙酸甲酯 | CAS号108-88-3 甲苯 | CAS号85981-82-4 1-(2-hydroperox... | CAS号108-38-3 间二甲苯 | CAS号611-01-8 2,4-二甲基苯甲酸 | CAS号842136-27-0 5-溴-2,4-二甲基苯甲酸 | CAS号293309-69-0 2,6-bis(2,4-dim... | CAS号1811-85-4 3-(2,4-二甲基苯基)丙酸 | CAS号21900-42-5 2,4-二甲基苯甲酰氯 | CAS号824-55-5 2,4-二甲基苄氯 | CAS号874-41-9 4-乙基间二甲苯 | CAS号102166-55-2 1,3-bis-(2,4-di... | CAS号528-44-9 1,2,4-苯三甲酸

合成工艺路线路线简述

    2-溴-1-(2,4-二甲基苯基)乙酮置于异丙苯,四丁基溴化铵体系中,化学反应 66.0H,以41%的收率获得产物2,4-二甲基苯乙酮
    参考文献:Trapping The Single Electron Transfer Intermediate In An Sn2 Reaction
    标题:Trapping The Single Electron Transfer Intermediate In An Sn2 Reaction
    摘要:
    DOI:10.1021/ja00116A053

    海关参考信息

    专利信息


    专利号:US-2022145179-A1
    优先权日:2020-11-12
    标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion
    发明人:MAZUMDER MOHAMMAD ABU JAFAR; ALI SHAIKH ASROF; ODEWUNMI NURUDEEN; ALHARBI BADER; ALJEABAN NORAH; CHEN TAO; BALHARTH SALEM
    权利人:SAUDI ARABIAN OIL CO; UNIV KING FAHD PET & MINERALS
    摘要:Methods for preparing alkenylphenone corrosion inhibiting compositions may include providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Corrosion inhibiting compositions may include an alkenylphenone, which may be prepared by a method including providing an arylacetone and reacting the arylacetone with formaldehyde in the presence of a strong base catalyst. Methods of inhibiting corrosion of a steel surface of an oilfield equipment component may include contacting the steel surface with an aqueous solution comprising a corrosion inhibitor. The corrosion inhibitor may include a composition containing an alkenylphenone prepared by reacting an arylacetone with formaldehyde in the presence of a strong base catalyst.

    专利号:WO-2022104049-A1
    优先权日:2020-11-12
    标题 :Synthesis of aryl 1-(methoxymethyl) vinyl ketones and their use as inhibitors of mild steel corrosion

    专利号:US-9163020-B2
    优先权日:2013-07-17
    标 题 :Azaindole compounds, synthesis thereof, and methods of using the same
    发明人:SHIRUDE PRAVIN S; NAIK MARUTI N; SHINDE VIKAS NARAYAN; PEER MOHAMED SHAHUL HAMEED; CHATTERJI MONALISA; SHINDIL RADHA K
    权利人:GLOBAL ALLIANCE FOR TB DRUG DEV; ASTRAZENECA AB; FOUNDATION FOR NEGLECTED DISEASE RES
    摘要:The invention provides compounds of formula (I) and methods of treating a Mycobacterium infection or tuberculosis, or inhibiting DprE1 with the same.

    专利号:US-8513241-B2
    优先权日:2008-03-28
    标题 :3,4-dihydro-2H-pyrazino[1,2-A]indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
    发明人:CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; SALOM BARBARA
    权利人:CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; SALOM BARBARA; NERVIANO MEDICAL SCIENCES SRL
    摘要:Compounds which are 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

    专利号:CA-2918487-A1
    优先权日:2013-07-17
    标 题 :Azaindole compounds, synthesis thereof, and methods of using the same

    专利号:US-2015025087-A1
    优先权日:2013-07-17
    标题 :Azaindole compounds, synthesis thereof, and methods of using the same
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Masahiko Nakamura, Et Al. Discovery Of Tetrahydrotetramethylnaphthalene Analogs As Adult T-Cell Leukemia Cell-Selective Proliferation Inhibitors In A Small Chemical Library Constructed Based On Multi-Template Hypothesis. Bioorg Med Chem. 2009 Jul 1;17(13):4740-6.

    合成参考文献


    摘要:Zysman-Colman, E., Science of Synthesis, (2010) 45, 189.
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