CAS: 7423-31-6; 1-Ethyl-2-(3-(1-Ethylnaphtho[1,2-D]Thiazol-2(1H)-Ylidene)-2-Methylprop-1-En-1-yl)Naphtho[1,2-D]Thiazol-1-Ium Bromide
该化合物是多种多功能的碳酸染料,常用于生物化学和组织学应用中,用于核酸,蛋白质和甘蓝氨基甘油的选择性染料. 它的广谱结合性使DNA(蓝色),RNA(红)和磷蛋白(净)在不同条件下得以区分. 染料对于检测低分子重量的硫化物和电光凝胶中的核酸特别有用,具有高度敏感性. 粉色-All也用于分析蛋白色, 因为它与硫酸和碳白酸组发生相互作用. 它在水溶剂和有机溶剂中的稳定性使得它适合不同的实验室协议. 推荐适当的处理和优化的染料条件,以产生可再生效果.
- 英文名称1-Ethyl-2-(3-(1-Ethylnaphtho[1,2-D]Thiazol-2(1H)-Ylidene)-2-Methylprop-1-En-1-yl)Naphtho[1,2-D]Thiazol-1-Ium Bromide
- 中文名称着色剂-ALL
- IUPAC名称1-ethyl-2-((1E,3Z)-3-(1-ethylnaphtho[1,2-d]thiazol-2(1H)-ylidene)-2-methylprop-1-en-1-yl)naphtho[1,2-d]thiazol-1-ium bromide
- 其它别名3,3'-Diethyl-9-Methyl-4,5,4',5'-Dibenzothiacarbocyanine ; Dbtc ; Carbocyanin Dbtc ; 1-Ethyl-2-[3-(1-Ethylbenzo[e][1,3]Benzothiazol-1-Ium-2-yl)-2-Methylprop-2-Enylidene]Benzo[e][1,3]Benzothiazole; Bromide ; 3,3'-Diethyl-9-Methyl-4,5,4',5'-Dibenzothiacarbocy
- CAS编号7423-31-6
- MFCD编号:MFCD00078788
- EINECS号:231-047-7
- FDA UNII编号:4MB06G6N2I
- 分子式:C30H27BrN2S2分子量:559.6
- 产品CID: 1731862
- 产品分类生物化工 → 生化试剂 → 生物染料
物理性质
- 熔点>200°C
- 沸点200°C>>200°C
- 闪点 °C
- 密度1.3339 (估算)
- PSA:65.29
- LogP:4.7203
- 溶解性Soluble In Water, Ethanol, Chloroform
- 敏感性光敏感
- 外观形态暗深紫色至深灰色暗紫色粉末
- 储存条件2-8°C
- 产品应用该化合物用作研究在CALUMOPLASIC RETICULUMM(CAM)和相关的钙结合蛋白质(CABPS)中个别钙结合点的结构特征,它有不同的污点,CA2+粘合蛋白蓝色,比COOMASSIE蓝色更敏感,检测这些蛋白.在骨骼肌肉提取物中,它污点大多数蛋白物,包括CA2(测量)/MG2+-ATPASE和53 000-DA(红或粉色)的碳酸盐(CALCOPROCULUSULUM),16万DA 甘油蛋白(C)和170 000-达蛋白是蓝色的.STAIN-ALLEN(测量量为615纳米)与COMASIE蓝色(测量为575纳米)的污点感应率为1.3,卡塞奎克林(CLOCHODOLDIN)为2.0,CROPONPIN为1.4,S-100蛋白2.2.
MSDS等安全信息
上下游产品
methyl dithioacetate 1-ethyl-2-methylnaphtho[1,2-d]thiazolium p-toluenesulphonate Triethyl orthoacetate合成工艺路线路线简述
📜1-乙基-2-甲基萘酚[1,2-D]对甲苯磺酸噻唑鎓盐,原乙酸三乙酯置于吡啶体系中,化学反应生成 着色剂-All
参考文献:真菌毒性研究 I.-某些碳花青的真菌毒性
标题:真菌毒性研究 I.-某些碳花青的真菌毒性
摘要:检查了 35 种碳菁的真菌毒性,发现其中一些具有活性.这种新发现的生物学特性仅限于分子量相当低的碳菁,并且依赖于衍生碳菁的杂环碱基.无论它们的位置如何,烷基取代基都增强了染料的真菌毒性.一些染料的测试表明,这些染料渗透到孢子的原生质体中,不可逆转地染色它们.
DOI:10.1002/jsfa.2740080711
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2901241000-1,3-丁二烯
2902902000-精萘 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-12006540-B2
优先权日:2015-09-28
标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
发明人：JU JINGYUE; LI XIAOXU; CHEN XIN; LI ZENGMIN; KUMAR SHIV; SHI SHUNDI; GUO CHENG; REN JIANYI; HSIEH MIN-KANG; CHIEN MINCHEN; TAO CHUANJUAN; ERTURK ECE; KALACHIKOV SERGEY; RUSSO JAMES J
权利人:UNIV COLUMBIA
摘要:Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.
专利号:US-2024376536-A1
优先权日:2015-09-28
标题 :Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis
专利号:US-2022411860-A1
优先权日:2015-09-28
标题:Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis
专利号:US-2023028388-A1
优先权日:2015-09-28
标 题 :Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis
专利号:CN-114989235-A
优先权日:2015-09-28
标题:Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis
专利号:US-11999999-B2
优先权日:2015-09-28
标 题 :Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
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品牌试剂参考报价(招募中)
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主要参考文献
1: Addotey JN, Lengers I, Jose J, Gampe N, Béni S, Petereit F, Hensel A. Isoflavonoids with inhibiting effects on human hyaluronidase-1 and norneolignan clitorienolactone B from Ononis spinosa L. root extract. Fitoterapia. 2018 Sep 1;130:169-174. doi: 10.1016/j.fitote.2018.08.013. [Epub ahead of print] doi: 10.1016/j.ijbiomac.2018.06.011. Epub 2018 Jun 8. doi: 10.1002/elps.201700391. Epub 2017 Nov 29. Epub 2016 Oct 24.
5: Kawashima A, Kigoshi T, Katoh Y, Ishikawa Y, Shawki HH, Inoue N, Tamba M, Matsuda M, Okamura N. CABCOCO1, a novel coiled-coil protein With calcium-binding activity, is localized in the sperm flagellum. Mol Reprod Dev. 2016 Oct;83(10):912-926. doi: 10.1002/mrd.22639. Epub 2016 Mar 28. doi: 10.4103/0973-029X.180925.
7: Wen S, Ma YX, Wu KS, Cui JT, Luo YB, Qu GQ. [Research on the Tomato Metacaspase Protein Interactions with Ca2+ by Spectroscopy and Molecular Probe]. Guang Pu Xue Yu Guang Pu Fen Xi. 2015 Jun;35(6):1643-8. Chinese. doi: 10.1016/j.bbrc.2015.09.170. Epub 2015 Oct 9. doi: 10.3390/molecules200915449. doi: 10.1002/elps.201500249. Epub 2015 Aug 21. doi: 10.1016/j.ab.2015.06.013. Epub 2015 Jul 4. doi: 10.1371/journal.pone.0128457. eCollection 2015.
合成参考文献
参考文献:10.1007/s00216-003-1753-0
摘要:Orlova NV, Proskurnin MA, Samburova VA, Dryagleva ID, Brusnichkin AV. The use of thermal lensing for the determination of pyrogens. Analytical and Bioanalytical Chemistry. 2003 Feb 28;375(8):1038–44. doi: 10.1007/s00216-003-1753-0.
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