CAS: 39692-63-2; Z-Dehydro-Ala-Oh

相似化合物

261522-33-2 21149-17-7 1138-80-3

上下游产品

O-benzyl carbamate 2-oxo-propionic acid methyl 2-(benzyloxycarbonylamino)acrylate methyl (R)-(+)-2-(benzyloxycarbonylamino)-3-chloropropionoateN-Benzyloxycarbonyl-2-mercapto-DL-alanin N-(Benxyloxycarbonyl)dehydroalanine benzyl ester 2-(2-Benzyloxycarbonylamino-acryloylamino)-3-hydroxy-butyric acid methyl ester benzyloxycarbonyldehydroalaninamide

📜N-(Benzyloxycarbonyl)-S-Methyl-L-Cysteine置于sodium Hydroxide,甲酸体系中,化学反应 2.0H,反应生成 Z-脱氢丙氨酸
参考文献:Nonenzymatic Cleavages Of Peptide Chains At The Cysteine And Serine Residues Through Their Conversion To Dehydroalanine (Dhal). Ii. The Specific Chemical Cleavage Of Cysteinyl Peptides
标题:Nonenzymatic Cleavages Of Peptide Chains At The Cysteine And Serine Residues Through Their Conversion To Dehydroalanine (Dhal). Ii. The Specific Chemical Cleavage Of Cysteinyl Peptides
摘要:
DOI:10.1021/ja01060A050

专利信息

专利号:US-4539151-A
优先权日:1983-06-29
标 题:Benzothiazepine derivatives and their method of preparation
发明人：KATAKAMI TSUTOMU; FUKAZAWA NOBUYUKI; IIZUKA HAJIME
权利人:MITSUI TOATSU CHEMICALS
摘要:This invention relates to benzothiazepine derivatives of the general formula ##STR1## where Y is hydrogen, a CHR 3 --COOR 1 group, an alkanoyl group or a --COO(CH 2 ) n R 4 group where R 1 is hydrogen or a lower alkyl group, R 3 is hydrogen, an alkyl group, an alkylphenyl group or an aryl-lower alkyl group, R 4 is an aryl group and n is a whole number of 1 to 10, and to their method of preparation. n The benzothiazepine derivatives of this invention, including their salts, have an inhibitory effect on the angiotensin converting enzyme and are useful as raw materials or intermediates for the synthesis of antihypertensive agents and as intermediates for the manufacture of other drugs, agricultural chemicals and industrial chemicals.