CAS: 25941-03-1; (3S,4S,5R,6R)-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetrayl Tetraacetate

该化合物是一种完全乙基的D-mannose衍生物,广泛用作碳水化合物化学和凝胶反应的关键中间体,其乙酰组提供稳定性,促进选择性脱保,使其对合成复杂的寡头细胞和玻璃合成具有价值.复合物表现出高度纯度和一致性的再活动,确保了甘合物的可靠性能.其晶体形式便于处理和储存.由于其定义明确的结构,它作为药用化学,糖基生物学研究以及碳水化合物基治疗方法开发的关键建筑块.该产品在温和条件下受控的甘代物结合形成过程中特别有用.

结构式图片

相似化合物

83-87-4 604-69-3 4163-65-9

欧盟法规

C&L通报

上下游产品

β-D-mannose acetic anhydride D-Mannose D-Mannose 1-O-p-nitrophenyl-2,3,4,6-tetra-O-acetyl α-D-mannopyranoside ethyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-mannopyranoside S-ethyl 2,3,4,6-tetra-O-acetyl-1-deoxy-1-thio-α-D-mannopyranoside 1-O-phenyl-2,3,4,6-tetra-O-acetyl-β-D-mannopyranoside

合成工艺路线路线简述

    📜D-葡萄糖 反应生成α-D-五乙酸甘露糖酯
    参考文献:Ichikawa,Shuji;Tomita,Isao;Hosaka,Akira;Sato,Tadashi,Bull. Chem. Soc. Jap.,61,(1988) N 2,513-520
    标题:Ichikawa,Shuji;Tomita,Isao;Hosaka,Akira;Sato,Tadashi,Bull. Chem. Soc. Jap.,61,(1988) N 2,513-520

    海关参考信息

    专利信息


    专利号:WO-9636627-A1
    优先权日:1995-05-19
    标 题 :Collection of activated glycoside compounds and their biological use
    发明人:ANDERSON MARK BRIAN; MUSSER JOHN H
    权利人:GLYCOMED INC
    摘要:The present invention relates to the field of combinatorial carbohydrate chemistry and involves the modification of organic molecules and/or the synthesis of large numbers of products comprising carbohydrate and/or glycominetic entities. More specifically, the present invention relates to activated carbon glycosides useful for the modification of organic molecules by incorporation of carbohydrate units, providing the synthesis of large numbers of products having novel chemical characteristics. The present invention further relates to methods for the generation of chemical compounds comprising carbon glycosides. Methods are disclosed to provide large arrays of molecules and to identify species that act as agonists or antagonists of various biological, chemical, and other activities.

    专利号:US-9777034-B2
    优先权日:2013-05-21
    标题 :Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes
    发明人:PERCEC VIRGIL
    权利人:UNIV PENNSYLVANIA
    摘要:The invention concerns compounds of the formula (I) wherein: Y 1 and Y 2 are independently a monosaccharide or disaccharide; X 1 and X 2 are independently —(R 9 —O) m —, —(R 10 ) p —, —O—(R 11 —O) q —, —R 16 —O—R 17 —O— or a covalent bond; Q 1 and Q 2 are independently a nitrogen-containing heterocycle moiety; Z 1 and Z 2 are independently —(O—R 7 )—, —(O—C(â•?O)—R 8 )a-, —O—C(â•?O)—R 12 —C(=0)-R 13 —, —O—C(â•?O)—R 14 —C(â•?O)—R 15 or a covalent bond; R 7 -R 17 are each independently C 1 -C 6 alkyl; R 1 -R 6 are each independently a linear or branched alkyl group; b, c, d, e, f, and g are 0 or 1, provided b+c+d equals at least 2 and e+f+g equals at least 2; and a, m, p, and q are each an integer from 1-6.

    专利号:RU-2165266-C1
    优先权日:2000-06-28
    标题 :Method of synthesis of [2-18f]-2-deoxyglucose

    专利号:US-2016108076-A1
    优先权日:2013-05-21
    标题:Modular synthesis of amphiphilic janus glycodendrimers and their self-assembly into glycodendrimersomes

    专利号:WO-2014190024-A1
    优先权日:2013-05-21
    标题 :Modular synthesis of amphiphilic janus glycodendrimers and their self-assembly into glycodendrimersomes

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:A Concise Synthesis Of Oligosaccharides Derived From Lipoarabinomannan (Lam) With Glycosyl Donors Having A Nonparticipating Group At C2
    作者:Zhihao Li,Changping Zheng,Marco Terreni,Teodora Bavaro,Matthieu Sollogoub,Yongmin Zhang |发布日期:2020.4.16
    摘要:Is One Of The Top Ten Leading Causes Of Death Over The World, And Lipoarabinomannan (Lam) Has Been Confirmed To Play Significant Roles In This Process. In This Study, A Convenient Synthetic Approach Has Been Developed For The Synthesis Of Oligosaccharides Derived From Lam Starting With Commercially Available Substrates And Reagents. The Key Steps For Stereoselective Construction Of Glycosidic Bonds By

    合成参考文献


    摘要:Kryczka, B.; Lewkowski, J.; Zawisza, A., Science of Synthesis, (2007) 29, 992.
    摘要:Kryczka, B.; Lewkowski, J.; Zawisza, A., Science of Synthesis, (2007) 29, 997.
    摘要:Robina, I.; Vogel, P., Science of Synthesis, (2008) 37, 755.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知