CAS: 2580-77-0; β-Hydroxyethyl Sulfone

相似化合物

2580-77-0 16002-30-5 123-45-5

上下游产品

CAS号111-48-8 硫双乙醇 | CAS号3085-45-8 THIODIGLYCOL SU... | CAS号471-03-4 Ethane,1,1'-sul... | CAS号7732-18-5 水 | CAS号7722-84-1 过氧化氢 | CAS号64-19-7 冰醋酸 | CAS号67-64-1 丙酮 | CAS号93-59-4 过氧化氢苯甲酰 | CAS号64-17-5 乙醇 | CAS号67-66-3 氯仿 | CAS号77-77-0 乙烯砜 | CAS号107-61-9 4,4-二氧-1,4-噻恶烷 | CAS号3763-72-2 2,2'-sulphonylb...

📜芥菜砜置于sodium Hydroxide,乙醇体系中,化学反应生成2,2'-磺酰基双乙醇
参考文献:Cashmore,Journal Of The Chemical Society,1923,Vol. 123,P. 1740
标题:Cashmore,Journal Of The Chemical Society,1923,Vol. 123,P. 1740

专利信息

专利号:US-5278266-A
优先权日:1991-02-06
标 题 :Synthesis of poly(vinyl phosphonic acid)
发明人：BRAYBROOK JULIAN H; ELLIS JOHN
权利人:BRITISH TECH GROUP
摘要:Poly(vinyl phosphonic acid) is synthesized by polymerizing vinyl phosphonyl dichloride in the presence of a cross-linker such as formaldehyde or 1,3-butadiene di-epoxide, with a free-radical initiator. The product can be reacted with aluminosilicate glass to form an improved cement.

专利号:US-8541569-B2
优先权日:2008-09-06
标题:Phosphoramidites for synthetic RNA in the reverse direction, efficient RNA synthesis and convenient introduction of 3'-end ligands, chromophores and modifications of synthetic RNA
发明人：SRIVASTAVA SURESH C; SRIVASTAVA NAVEEN P
权利人:SRIVASTAVA SURESH C; SRIVASTAVA NAVEEN P; CHEMGENES CORP
摘要:The present invention provides building blocks and methods for synthesizing very pure RNA in a form that can efficiently be modified at the 3′ end. Reverse RNA monomer phosphoramidites have been developed for RNA synthesis in 5′→3′ direction, leading to very clean oligo synthesis that allows for the introduction of various modifications at the 3′-end cleanly and efficiently. Higher coupling efficiency per step have been observed during automated oligo synthesis with the reverse RNA amidites disclosed herein, resulting in a greater ability to achieve higher purity and produce very long oligonucleotides. The use of the reverse RNA phosphoramidites in the synthetic process of this invention leads to oligonucleotides free of N+1 species.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:US-2003036066-A1
优先权日:2000-09-08
标 题:Linker phosphoramidites for oligonucleotide synthesis
发明人：PON RICHARD T; YU SHUYAN
权利人:UNIV TECHNOLOGIES INT
摘要:A novel approach for combining the ease of cleavage of carboxylic acid linker arms with the single phosphoramidite coupling chemistry of the universal supports useful in oligonucleotide synthesis. There is disclosed a new class of phosphoramidite reagents, linker phosphoramidites, which contain a bifunctional linker arm with a protected nucleoside linked through a 3′-ester bond on one end and a reactive phosphoramidite group or other phosphate precursor group on the other end—see FIGS. 2 and 3. The phosphoramidite group on the linker phosphoramidite may be activated under the same conditions and has similar reactivity as conventional nucleoside-3′-phosphoramidite reagents lacking the intermediate linker arm. The 3′-ester linkage contained within the linker phosphoramidite has similar properties to the linkages on prederivatized supports. The ester linkage is stable to all subsequent synthesis steps, but upon treatment with a cleavage reagent, such as ammonium hydroxide, the ester linkage is hydrolyzed. This releases the oligonucleotide product with the desired 3′-hydroxyl terminus and leaves the phosphate portion of the reagent attached to the support, which is subsequently discarded.

专利号:JP-H10508827-A
优先权日:1994-08-17
标 题 :Solid support reagents for the synthesis of 3 'nitrogen-containing polynucleotides

专利号:WO-9320092-A1
优先权日:1992-04-03
标题 :Synthesis of oligonucleotides