CAS: 2216-45-7; 4-Methylbenzyl Acetate

该化合物是一种该化合物是一种有价值的中间体.在典型的储存条件下,该化合物具有良好的稳定性,与一系列溶剂相容,在工业应用中增强了其多功能性.其清晰,无色的液体形式确保了处理和融入各种配方的便利性.乙酸酯组促成其适度的波动性,使之适合用于香水和化妆品中需要均衡蒸发特征的成分.其一贯的纯度和明确界定的化学特性支持了专门应用的可靠性能.

结构式图片

上下游产品

CAS号589-18-4 4-甲基苄醇 | CAS号108-24-7 乙酸酐 | CAS号64-19-7 冰醋酸 | CAS号106-42-3 对二甲苯 | CAS号141-78-6 乙酸乙酯 | CAS号75-36-5 乙酰氯 | CAS号108-05-4 乙酸乙烯酯 | CAS号104-87-0 对甲基苯甲醛 | CAS号79-20-9 乙酸甲酯 | CAS号108-22-5 醋酸异丙烯酯 | CAS号589-18-4 4-甲基苄醇 | CAS号3006-96-0 4-羟甲基苯甲酸 | CAS号15561-46-3 4-[(乙酰氧基)甲基]-苯甲酸 | CAS号619-66-9 对醛基苯甲酸 | CAS号14720-70-8 acetic acid,[4-... | CAS号54549-74-5 Acetic acid 4-f... | CAS号104-87-0 对甲基苯甲醛 | CAS号99-94-5 对甲基苯甲酸

合成工艺路线路线简述

  • 合成目标产物 4-Methylbenzyl Acetate 主要起始原料 4-Methylbenzyl Alcohol And Ethyl Acetate
  • (文献来源)合成步骤主要原料 4-Methylbenzyl Alcohol 和 Ethyl Acetate
对二甲苯置于lead(Iv) Acetate,溶剂黄146体系中,化学反应生成乙酸对甲基苄酯
参考文献:有机氧化过程.第二部分 四乙酸铅与甲苯及相关化合物的反应
标题:有机氧化过程.第二部分 四乙酸铅与甲苯及相关化合物的反应
摘要:
Doi:10.1039/jr9540003943

海关参考信息

专利信息


专利号:US-6423877-B1
优先权日:1999-11-15
标题:Synthesis of pseudopterosin compounds
发明人:COREY ELIAS J
权利人:HARVARD COLLEGE
摘要:The present invention is directed to a new synthetic route to pseudopterosin aglycone (3): n a key intermediate for the synthesis of a group of antiinflammatory natural products including pseudopterosin A (1) and E (2). The pathway of synthesis starts with the abundant and inexpensive (S)-(−)-limonene and its long-known cyclic hydroboration product (4) and leads to the chiral hydroxy ketone (6). Conversion of (6) to (10) followed by a novel aromatic annulation produced (15) which underwent highly diastereoselective cyclization to afford the protected pseudopterosin aglycone (16). The naturally occurring pseudopterosins such as (1) and (2) are readily available from this key intermediate.

专利号:US-8106031-B2
优先权日:2006-05-02
标题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-10287225-B2
优先权日:2015-05-13
标 题:Chain multiyne compound, preparation method and application thereof
发明人:XIA HAIPING; ZHUO QINGDE; LIN JIANFENG; ZHOU XIAOXI; CHEN ZHIXIN; SHAO YIFAN; ZHANG HONG; HE XUMIN
权利人:UNIV XIAMEN
摘要:The present invention relates to fields of organic chemistry and organometallic chemistry. The present invention discloses a chain multiyne compound, a preparation method thereof and an application in synthesizing a fused-ring metallacyclic compound. A structure of the chain multiyne compound in the present invention is shown as Formula I below. The present invention also provides a preparation method of the chain multiyne compound and an application thereof in a synthesis of a fused-ring metallacyclic compound. The chain multiyne compound disclosed in the present invention has multiple functional groups and the structure of the chain multiyne compound is adjustable. The chain multiyne compound can also be used to synthesize the fused-ring metallacyclic compound efficiently. The preparation method of the chain multiyne compound disclosed in the present invention is simple, which can be used to prepare the chain multiyne compound rapidly and efficiently.

专利号:US-9707301-B2
优先权日:2011-10-14
标题 :Pyrrolobenzodiazepines and targeted conjugates
发明人:JEFFREY SCOTT; BURKE PATRICK; HOWARD PHILIP WILSON
权利人:SEATTLE GENETICS INC; MEDIMMUNE LTD
摘要:This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates.

专利号:GB-2080335-A
优先权日:1980-07-15
标题 :Electrochemical synthesis of organic compounds

专利号:EP-2558445-B1
优先权日:2010-04-15
标 题 :Intermediates useful for the synthesis of pyrrolobenzodiazepines
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主要参考文献


1: Kano K, Kitae T, Shimofuri Y, Tanaka N, Mineta Y. Complexation of polyvalent cyclodextrin ions with oppositely charged guests: entropically favorable complexation due to dehydration. Chemistry. 2000 Aug 4;6(15):2705-13. R., McKeon, J. E., & Ream, B. C. (1968). Palladium-catalyzed synthesis of benzyl esters from methyl-benzenes. The Journal of Organic Chemistry, 33(11), 4123-4127.
3: Field, F. H. (1969). Chemical ionization mass spectrometry. X. Temperature studies with substituted benzyl acetates. Journal of the American Chemical Society, 91(23), 6334-6341.
4: Okada, T., & Kamiya, Y. (1981). The liquid-phase oxidation of methylbenzenes by the cobalt-copper-bromide system. Bulletin of the Chemical Society of Japan, 54(9), 2724-2727.

合成参考文献


摘要:Gosmini, C.; Corpet, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 690.
参考文献:10.1038/nchem.1506
摘要:Over B, Wetzel S, Grütter C, Nakai Y, Renner S, Rauh D, Waldmann H. Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem. 2013 Jan;5(1):21–8. doi: 10.1038/nchem.1506.
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