专利号:US-11912654-B2 优先权日:2021-09-03 标 题:Process for stereospecific synthesis of vitamin K2 and its novel intermediates 发明人:MEHTA DILIP; SHASHTRI MAYANK; RAJU BNS; SHAH ASHWIN; VORA PARIN; MAHALE UMAKANT 权利人:SYNERGIA LIFE SCIENCES PVT LTD 摘要:The present disclosure relates to a novel process for the synthesis of stereospecific compounds of Vitamin K2 group in general and Vitamin K2-7. The present disclosure further discloses novel intermediates useful in the synthesis of stereospecific Vitamin K2-7. Compounds of the Vitamin K2 group obtained are crystalline and exhibit well defined melting points.
专利号:US-8822187-B1 优先权日:2011-04-27 标题:Polypeptides, nucleic acid molecules, and methods for synthesis of triterpenes 发明人:CHAPPELL JOE; NIEHAUS THOMAS D; OKADA SHIGERU; DEVARENNE TIMOTHY P; WATT DAVID S 权利人:CHAPPELL JOE; NIEHAUS THOMAS D; OKADA SHIGERU; DEVARENNE TIMOTHY P; WATT DAVID S; UNIV KENTUCKY RES FOUND 摘要:This application relates to the polypeptides, nucleic acid molecules, vectors, transfected cells, and methods for synthesis of triterpenes, including botryococcene.
专利号:US-3674818-A 优先权日:1969-12-05 标 题:Synthesis of a material with juvenile hormone activity 发明人:LAW JOHN H 权利人:US HEALTH EDUCATION & WELFARE 摘要:Synthesis of a material with juvenile hormone activity by reacting crude or purified farnesoic acid with alcoholic hydrogen chloride wherein the alcohol is selected from the group consisting of ethanol, methanol, n-propanol and n-pentanol. Various comparisons are shown with other related compounds and an exemplary list of insects sensitive to the material is set forth.
专利号:US-7541172-B2 优先权日:1998-08-27 标题:Transgenic amorpha-4, 11-diene synthesis 发明人:WALLAART THORVALD EELCO; BOUWMEESTER HENDRIK JAN 权利人:INST ONEWORLD HEALTH 摘要:The present invention relates to an isolated DNA sequence encoding a polypeptide having the biological activity of amorpha-4,11-diene synthase. This DNA sequence can be used for the transformation of bacteria, yeasts and plants for the production of amorpha-4,11-diene, a specific precursor in the synthesis of artemisinin, in the respective organisms. The invention also relates to these organisms.
专利号:US-9464021-B2 优先权日:2013-11-01 标题 :Method of preparation of stereospecific quinone derivatives 发明人:MEHTA DILIP S; MOHAN PRIYA; SHASTRI MAYANK; REID TED 权利人:MEHTA DILIP S; MOHAN PRIYA; SHASTRI MAYANK; REID TED 摘要:The description provides processes for the regio and stereospecific synthesis of polyprenylatedquinone derivatives, such as Vitamin K1, K2 and Ubiquinone, exploiting dithioacetals, especially 1,3-dithiane, mediated Umpolung chemistry which works along a new concept “Inhibiting resonance delocalization (IRD)â€? to overcome isomerization generated due to delocalization of allyliccarbanion on the Ï€-electron cloud of an allylic systems by the conventional synthesis.
专利号:US-2008200733-A1 优先权日:2005-07-06 标 题 :Processes For The Preparation Of Purified Solanesol, Solanesyl Bromide & Solanesyl Acetone 发明人:UPARE ABHAY; WAGH GANESH; CHAVAN AMIT; JAFRI WAZID SAJJAD; SELVAKUMAR SABAPATHI; ROY MITA 权利人:NICHOLAS PIRAMAL INDIA LTD 摘要:The present invention relates to processes for the preparation of purified solanesol, solanesyl bromide & solanesyl acetone. Solanesyl acetone has the chemical name—all—trans 6,10,14,18,22,26,30,34,38-nonamethyl-5,9,13,17,21,25,29,33,37-triacontanonaen-2-one, of formula 1 and is used for synthesis of coenzyme Q 10 .
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合成参考文献
参考文献:10.4161/psb.6.8.15772 摘要:Fitzpatrick AH, Shrestha N, Bhandari J, Crowell DN. Roles for farnesol and ABA in Arabidopsis flower development. Plant Signaling & Behavior. 2011 Aug;6(8):1189–91. doi: 10.4161/psb.6.8.15772. 参考文献:10.1038/ja.2011.49 摘要:Kaneko M, Togashi N, Hamashima H, Hirohara M, Inoue Y. Effect of farnesol on mevalonate pathway of Staphylococcus aureus. J Antibiot (Tokyo). 2011 Aug;64(8):547–9. doi: 10.1038/ja.2011.49.