CAS: 10022-13-6; 1,3,4,6-Tetra-O-Acetyl-2-Deoxy-2-Phthalimido-ß-D-Glucopyranose
该化合物是甘蔗的合成衍生物,其特点是存在多种乙酰组和二氟硫酸盐.该化合物的特点是一种甘蓝糖环,这是六人环状甘蔗糖的一种六人组成的循环甘蓝,在二层配有二人组进行修改,增加了其在有机溶剂中的再活性和溶性.1,3,4和6个方位的乙酰群为保护氢氧基组提供了保护,使化合物更加稳定,并促进了各种化学反应.它通常用于有机合成,特别是用于制作甘油捐献者进行玻璃相合反应.这种硫酸酯组的存在也可以影响该化合物的生物活动,使其对药用化学感兴趣.总体而言,这种化合物是碳水酸盐化学中有价值的中间体,在合成更为复杂的甘油和其他碳水化合物衍生物时应用.
- 英文名称1,3,4,6-Tetra-O-Acetyl-2-Deoxy-2-Phthalimido-ß-D-Glucopyranose
- 中文名称2-脱氧-2-苯二酰亚胺-1,3,4,6-四-氧-乙酰-β-D-吡喃葡萄糖
- IUPAC名称(2S,3R,4R,5S,6R)-6-(acetoxymethyl)-3-(1,3-dioxoisoindolin-2-yl)tetrahydro-2H-pyran-2,4,5-triyl triacetate
- 其它别名Glucopyranose,2-deoxy-2-phthalimido-, 1,3,4,6-tetraacetate, b-D- (8CI); b-D-Glucopyranose, 2-deoxy-2-phthalimido-,1,3,4,6-tetraacetate (6CI); 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranose
- CAS编号10022-13-6
- MFCD编号:MFCD00080781
- 分子式:C22H23NO11分子量:477.42
- 产品CID: 6570
- 产品分类生物化工 → 糖类化合物 → 单糖
物理性质
上下游产品
O-acetyl-2-(2-carboxy-benzoylamino)-2-deoxy-β-D-glucopyranosetetra-O-acetyl-2-(2-carboxy-benzoylamino)-2-deoxy-β-D-glucopyranose chloroform chloroformic acid ethyl ester triethylamine phenyl 3,4,6-tri-O-acetyl-2-deoxy-2-N-phthalimido-β-D-glucopyranoside Benzyl-2-acetamido-3,6-di-O-benzyl-2-desoxy-4-O-(3,4,6-tri-O-acetyl-2-desoxy-2-phthalimido-β-D-glucopyranosyl)-α-D-glucopyranosid methyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside phenyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside合成工艺路线路线简述
- 合成目标产物 1,3,4,6-Tetra-O-Acetyl-2-Deoxy-2-Phthalimido-Beta-D-Glucopyranose 主要起始原料 β-D-Glucopyranose, 2-Deoxy-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-yl)- And Acetic Anhydride
- (文献来源)合成步骤主要原料 β-D-Glucopyranose, 2-Deoxy-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-yl)- 和 Acetic Anhydride
📜D-氨基葡萄糖盐酸盐置于吡啶,Sodium Methylate体系中,用 甲醇 用作溶剂,化学反应 21.0H,反应生成2-脱氧-2-苯二酰亚胺-1,3,4,6-四-氧-乙酰-β-D-吡喃葡萄糖
参考文献:Synthesis Of Oligonucleotides With Glucosamine At The 3'-Position And Evaluation Of Their Biological Activity
标题:Synthesis Of Oligonucleotides With Glucosamine At The 3'-Position And Evaluation Of Their Biological Activity
摘要:Short Interfering Rna (Sirna) Has Been Proven To Be An Utilizable Tool For Post-Transcriptional Gene Silencing Research. In This Study,We Designed And Synthesized Two Glucosamine Analogues And Tried To Modify The Sirna Using These Two Glucosamine Analogues At The 3'-Overhang Region Of Sirnas To Improve The Nuclease Resistance And To Overcome Some Other Weak Points. The Sirnas Modified With Glucosamine Analogues Had Almost No Effect Of The Thermal Stability And Showed Strong Resistance To Nuclease Degradation. Some Of Them Kept The Same Gene Silencing Activity Level As Unmodified Sirna. (C) 2013 The Authors. Published By Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2013.05.036
海关参考信息
- 2905399001-1,3-丙二醇
2905399002-1,4-丁二醇
2905450000-丙三醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Studies Directed To The Synthesis Of Oligochitosans - Preparation Of Building Blocks And Their Evaluation In Glycosylation Studies作者:Signe Grann Hansen,Troels Skrydstrup |发布日期:2007.7
摘要:And Pyridine In Dichloromethane. The Efficacy Of These Thioglycosides Both As Donors And Acceptors For The Construction Of Chitosans Was Evaluated. Whereas, The Thioglycosides Could Be Easily Coupled To Simple Alcohols In Excellent Yields Using The Glycosylation Promoting System N-Iodosuccinimide And Tms Triflate, These Conditions Could Not Effectuate Coupling To The C4-Hydroxy Group Possessing Flanking
合成参考文献
摘要:Turnbull, W. B.; Fascione, M. A.; Stalford, S. A., Science of Synthesis, (2007) 29, 948.
📝 需求与反馈
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