CAS: 636-00-0; 6-Hydroxydopamine Hydrobromide
该化合物是一种化学化合物,其结构特征包括一个含有三个氢氧基组(三醇)和氨基乙基侧链的苯环,该化合物的存在表明,该化合物是一种盐,由氢溴酸形成,提高了其在水中的溶解性.该化合物通常用于各种化学合成,并可能表现出氨基生物活动,因为氨基生物组可以参与各种生物化学相互作用.氢氧基组有助于其作为减少剂的潜力,并可能影响其再活性和溶性.此外,该化合物的特性,如熔点,沸点和稳定性,可以因环境条件和其他物质的存在而变化.与许多有机化合物一样,在处理时应采取安全防范措施,因为如果浸入或吸入,可能会对健康造成风险.始终提及具体处理和储存准则的安全数据表.
- 英文名称6-Hydroxydopamine Hydrobromide
- 中文名称6-羟基多巴胺合溴化氢
- IUPAC名称2,4,5-Trihydroxyphenethylamine hydrobromide
- 其它别名1,2,4-Benzenetriol,5-(2-aminoethyl)-, hydrobromide (6CI,7CI,8CI,9CI); 2-(2,4,5-Trihydroxyphenyl)ethylaminehydrobromide; 6-Hydroxydopamine hydrobromide; 6-Hydroxydopamine hydrogenbromide
- CAS编号636-00-0
- MFCD编号:MFCD00012894
- EINECS号:211-247-0
- FDA UNII编号:TWC1D4W0WB
- 分子式:C8H12BrNO3分子量:250.09
- 产品CID: 1617780
- 同类组份化合物CAS1199-18-4 (free base)636-00-0 (HBr)28094-15-7 (HCl)
- 产品分类生物化工 → 氨基酸及其衍生物 → 氨基醇类衍生物
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号3131-52-0 5,6-二羟基吲哚合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2907210001-间苯二酚
2907221000-对苯二酚
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专利信息
专利号:CN-115612114-A
优先权日:2021-07-14
标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis
专利号:US-2013236964-A1
优先权日:2002-11-17
标 题:Methods, nucleic acid constructs and cells for treating neurodegenerative disorders
发明人：MELAMED ELDAD; OFFEN DANIEL; LEVY YOSEF; GREEN PNINA
权利人:UNIV RAMOT
摘要:A method of treating a neurodegenerative disorder is provided. The method is effected by administering to an individual in need thereof cells capable of exogenously regulatable neurotransmitter synthesis thereby treating the neurodegenerative disorder.
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主要参考文献
1: Pantic I, Cumic J, Skodric SR, Dugalic S, Brodski C. Oxidopamine and oxidative stress: Recent advances in experimental physiology and pharmacology. Chem Biol Interact. 2021 Feb 25;336:109380. doi: 10.1016/j.cbi.2021.109380. Epub 2021 Jan 13. 11(3-4):151-67. doi: 10.1007/BF03033565. 32(8):533-539. English, Spanish. doi: 10.1016/j.nrl.2015.06.011. Epub 2015 Aug 21. 73(1):45-8. doi: 10.1016/s0165-0270(96)02211-x.
406:124-8. doi: 10.1016/j.jtbi.2016.07.018. Epub 2016 Jul 16. 8(1):15349. doi: 10.1038/s41598-018-33778-0.
7: Varešlija D, Tipton KF, Davey GP, McDonald AG. 6-Hydroxydopamine: a far from simple neurotoxin. J Neural Transm (Vienna). 2020 Feb;127(2):213-230. doi: 10.1007/s00702-019-02133-6. Epub 2020 Jan 1. 35(8):840-848. doi: 10.1002/tox.22920. Epub 2020 Mar 13. 16(2):63-77. doi: 10.1097/00008877-200503000-00001. 127(2):231-250. doi: 10.1007/s00702-020-02152-8. Epub 2020 Feb 6.
合成参考文献
参考文献:10.1007/bf00335780
摘要:Baumgarten HG, Holstein AF, Owman C. Auerbach's plexus of mammals and man: electron microscopic identification of three different types of neuronal processes in myenteric ganglia of the large intestine from rhesus monkeys, guinea-pigs and man. Z Zellforsch Mikrosk Anat. 1970;106(3):376–97. doi: 10.1007/bf00335780.
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