CAS: 625-33-2; Pent-3-En-2-One

该化合物是五碳链,第一和第二碳之间双联,第二碳中一氯酮功能组,该化合物一般无色可粉黄,具有典型的气味,在乙醇和乙醚等有机溶剂中溶解,但因其疏水性而在水中溶解性有限. 3-Penten-2-1,因其活动性而闻名,特别是在Michael附加反应和其他核本性添加物,使其在有机合成中具有价值.该化合物可作为生产各种化学品的中间体,包括制药和农用化学品.此外,该化合物可能具有某种程度的毒性,应在实验室环境中谨慎处理,其物理特性,如沸点和密度,可因环境条件和纯度而不同而不同.

结构式图片

相似化合物

3102-33-8 5166-53-0 1569-50-2

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

2-Methyl-4,5-dihydrofuran pent-4-en-2-one Cyclopropyl methyl ketone propene methyl-ethyl-propenyl-carbinol 4-methylhexan-2-one 4-methyl-2-pentanone 2-methyl-pent-3-en-2-ol

合成工艺路线路线简述

  • 合成目标产物 3-Penten-2-One 主要起始原料 Diethyl (2-Oxopropyl)Phosphonate And Acetaldehyde
  • 930-27-8 = 625-33-2 + 930-18-7 + 120-92-3 + 6108-61-8
    反应条件:1.1 Reagents: Hydrogen; 2 Mpa,600 °C
    标题:Understanding Cellulose Pyrolysis Under Hydrogen Atmosphere
    作者:Li,Tan; Miao,Kai; Zhao,Zhigang; Li,Yuqing; Wang,Huiyuan; Et Al
    参考文献:Energy Conversion And Management 日期:2022 卷标:254
4-Bromo-Pentan-2-One置于potassium Hydrogencarbonate体系中,化学反应生成 3-戊烯-2-酮
参考文献:Blaise,Bulletin De La Societe Chimique De France,1905,Vol. <3>33,P. 43
标题:Blaise,Bulletin De La Societe Chimique De France,1905,Vol. <3>33,P. 43

海关参考信息

专利信息


专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-5545568-A
优先权日:1992-09-14
标题:Solid phase and combinatorial synthesis of compounds on a solid support
发明人:ELLMAN JONATHAN A
权利人:UNIV CALIFORNIA
摘要:Methods, compositions, and devices for synthesizing combinatorial libraries of various useful compounds, such as benzodiazepines, prostaglandins, β-turn mimetics and glycerol-derived drugs is described. In order to expediently synthesize such combinatorial libraries of derivatives based upon these core structures, a general methodology for the solid phase synthesis of these derivatives is also provided. This disclosure thus also describes an important extension of solid phase synthesis methods to nonpolymeric organic compounds.

专利号:US-7112700-B1
优先权日:2005-04-14
标 题 :Efficient and economic asymmetric synthesis of nootkatone, tetrahydronootkatone, their precursors and derivatives
发明人:SAUER ANNE M; CROWE WILLIAM E; LAINE ROGER A; HENDERSON GREGG
权利人:UNIV LOUISIANA STATE
摘要:An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed. The starting materials used in the synthesis are inexpensive. The principal starting material, (−)-β-Pinene, is on the GRAS list (generally recognized as safe).

专利号:US-6951878-B2
优先权日:1998-03-12
标 题:Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases)
发明人:MOELLER NIELS PETER HUNDAHL; ANDERSEN HENRIK SUNE; IVERSEN LARS FOGH; OLSEN OLE HVILSTED; BRANNER SVEN; HOLSWORTH DANIEL DALE; BAKIR FARID; JUDGE LUKE MILBURN; AXE FRANK URBAN; JONES TODD KEVIN; RIPKA WILLIAM CHARLES; GE YU; UYEDA ROY TERUYUKI
权利人:NOVO NORDISK AS
摘要:The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. n The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.

专利号:US-2014245658-A1
优先权日:2013-02-08
标 题 :Synthesis of ethanol and higher alcohols by hydrogenation of ketene
发明人:HENRI JOHN T; ZYGMUNT JAN; BERGGREN MARK; ZUBRIN ROBERT
权利人:PIONEER ENERGY INC
摘要:Ketene chemistry and hydrogenation reactions are used to synthesize fuels and chemicals. Ketene from acetic acid is hydrogenated to form fuels and chemicals; acetic acid can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc. In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass.
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主要参考文献

参考标题:Synthesis Of γ-Sulfur-Substituted Ketones Via Rh(II)/sc(III) A Cocatalyzed Three-Component Reaction Of Diazo Compounds With Thiophenols And Enones
作者:Guolan Xiao,Chaoqun Ma,Xiang Wu,Dong Xing,Wenhao Hu |发布日期:2018.4.20
摘要:A Facile Method For The Synthesis Of γ-Sulfur-Substituted Ketones Is Developed Via A Rh(II)/sc(III) Cocatalyzed Three-Component Reaction Of Diazo Compounds With Thiophenols And Enones. With This Method, Different γ-Sulfur-Substituted Ketones Were Obtained In Moderate To High Yields With Good Diastereoselectivities.

合成参考文献


参考文献:10.1007/s10886-006-9091-2
摘要:Röck F, Mueller S, Weimar U, Rammensee H, Overath P. Comparative Analysis of Volatile Constituents from Mice and their Urine. Journal of Chemical Ecology. 2006 May 31;32(6):1333–46. doi: 10.1007/s10886-006-9091-2.
参考文献:10.1107/s1600536810045691
摘要:He L. Diethyl 4-acetyl-5-(2-nitro-phen-yl)pyrrolidine-2,2-dicarboxyl-ate. Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 17;66(Pt 12):o3205.
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