专利号:US-5981239-A 优先权日:1997-09-24 标 题 :Synthesis of optically active phenylalanine analogs using Rhodotorula graminis 发明人:LIU WEIGUO 权利人:GREAT LAKES CHEMICAL CORP 摘要:A biocatalytic process to produce optically active phenylalanine analogs from arylacrylic acids is disclosed in which Rhodotorula graminis yeast containing phenylalanine ammonia-lyase introduces a molecule of ammonia stereoselectively onto the double bond of a 3-substituted acrylic acid. The substituent at the 3-position of the 3-substituted acrylic acid includes, for example, aromatic rings such as substituted phenyl groups, five member aromatic heterocyclics, and six member aromatic heterocyclics.
专利号:WO-2016086015-A1 优先权日:2014-11-25 标 题:Myoglobin-based catalysts for carbene transfer reactions 发明人:FASAN RUDI 权利人:UNIV ROCHESTER; FASAN RUDI 摘要:Methods are provided for carrying out carbene transfer transformations such as olefin cyclopropanation reactions, carbene heteroatom-H insertion reactions (heteroatom = N, S, Si), sigmatropic rearrangement reactions, and aldehyde olefination reactions with high efficiency and selectivity by using a novel class of myoglobin-based biocatalysts. These methods are useful for the synthesis of a variety of organic compounds which contain one or more new carbon-carbon or carbon-heteroatom (N, S, or Si) bond. The methods can be applied for conducting these transformations in vitro (i.e., using the biocatalyst in isolated form) and in vivo (i.e., using the biocatalyst in a whole cell system).
专利号:CA-2283376-A1 优先权日:1997-09-24 标 题:Synthesis of optically active phenylalanine analogs through microbial transformations
专利号:EP-1085095-A1 优先权日:1997-09-24 标 题:Synthesis of optically active phenylalanine analogs through microbial transformations
专利号:CN-114230519-B 优先权日:2021-12-06 标题:A class of pleuromutilin cinnamate compounds with anti-drug-resistant bacteria activity and synthesis method and application thereof
专利号:CN-114230519-A 优先权日:2021-12-06 标 题:A class of pleuromutilin cinnamate compounds with anti-drug-resistant bacteria activity and its synthesis method and application
摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 201. 摘要:Vashchenko, B. V.; Grygorenko, O. O., Science of Synthesis Knowledge Updates, (2021) 3, 329.