专利号:US-2005202459-A1 优先权日:2003-09-23 标 题 :Intercalation-mediated synthesis of polymers
专利号:US-7368560-B2 优先权日:2003-09-23 标题:Intercalation-mediated synthesis of polymers 发明人:HUD NICHOLAS V 权利人:GEORGIA TECH RES INST 摘要:Methods and compositions for synthesizing biopolymers using an intercalator are provided. Aspects provide compositions and methods for synthesizing biopolymers with non-natural backbones or non-natural biopolymer subunits using natural biopolymer templates. Other aspects provide compositions and methods for synthesizing biopolymers using a template with a non-natural backbone on non-natural biopolymer subunits.
专利号:US-3914424-A 优先权日:1973-01-30 标题 :Method for treating P-388 or L-1210 leukemia strains 发明人:ZEE-CHENG KWANG YUEN; CHENG CHIA-CHUNG 权利人:US HEALTH 摘要:A process for the synthesis of coralyne salts and related dehydroberbinium salts. The process includes a phenylacetyl chloride and phenylethylamine condensation, followed by cyclization, aromatization and formation of a dehydroberbinium sulfoacetate, which may thereafter be converted into other dehydroberbinium salts. The coralyne salts have antineoplastic activity.
专利号:WO-9727206-A1 优先权日:1996-01-26 标 题:Oligonucleotide analogs 发明人:KHORLIN ALEXANDER A; WATANABE KYOICHI A 权利人:CODON PHARMACEUTICALS INC 摘要:Macromolecules are disclosed which contain the structure (1) wherein the substituents are defined in the specification. Also disclosed are compounds useful in the synthesis of the above compounds, as well as pharmaceutical compositions containing the above compounds as an active ingredient.
专利号:US-2003198960-A1 优先权日:2002-04-01 标 题 :Signal amplifying targeted reporters for biological and chemical sensor applications 发明人:FAN WENHONG; LI JUN; HAN JIE 摘要:The present invention provides targeted dendrimeric reporter molecules that provide amplified signals at electrochemical sensors, and methods of synthesis and methods of use thereof. The reporter molecules comprise a targeting moiety and at least one dendritic signal amplifier; the dendritic amplifier comprises a plurality of dendritic branches and a plurality of indicator moieties, typically pendant therefrom. The targeting moiety serves to concentrate the dendritic amplifier at a selected target, where the plural indicator provide increased signals.
1: Padmapriya K, Barthwal R. Nuclear magnetic resonance based structure of the protoberberine alkaloid coralyne and its self-association by spectroscopy techniques. J Pharm Anal. 2019 Dec;9(6):437-448. doi: 10.1016/j.jpha.2019.09.006. Epub 2019 Sep 26. 2: Ma C, Chen M, He H, Chen L. Detection of coralyne and heparin by polymerase extension reaction using SYBR Green I. Mol Cell Probes. 2019 Aug;46:101423. doi: 10.1016/j.mcp.2019.101423. Epub 2019 Jul 16. 120(10):18104-18116. doi: 10.1002/jcb.29114. Epub 2019 Jun 6. 194:140-148. doi: 10.1016/j.jphotobiol.2019.03.011. Epub 2019 Mar 21.
合成参考文献
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