专利号:US-5539117-A 优先权日:1993-04-13 标题:2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines 发明人:SNOW ROBERT A; DELECKI DANIEL J; SHAH CHANDRA R; HOLLISTER K ROBERT 摘要:The present invention is directed to 2-acetyl-6-cyanopyridine compounds that are useful as intermediates in the synthesis of oligo-2,6-pyridines. The present invention is also directed to new, simpler, less expensive methods for synthesizing such oligopyridines using the novel 2-acetyl-6-cyanopyridine compounds as intermediates.
专利号:US-2018111938-A1 优先权日:2015-05-05 标 题:Synthesis of Intermediates Used in the Manufacture of Anti-HIV Agents 发明人:PRADHAN BRAJA SUNDAR; AMARNATH KOMMIREDDY; VEMPALA NARESH; RAHMAN MD ATAUR 权利人:CBZ INVEST LTD 摘要:The present invention relates to a process of preparing intermediates of Formula (I). The process comprises of reacting compound of Formula (III) with compound of Formula (V) in the presence of a solvent selected from an alcohol, ether or water to form compound of Formula (I) wherein, R 1 is selected from —NH 2 , Cl, Br, NHCOR″, wherein R″ is alkyl, aryl, Schiff's base of formula Nâ•?CHR′, wherein R′ is alkyl or aryl; R 2 is selected from H, alkyl; R 3 and R 4 , each independently is H; R 5 and R 6 , each independently is H, alkyl; R 7 is H, alkyl; and R 8 is H, alkyl.
专利号:DE-1924135-A1 优先权日:1968-05-15 标 题:Synthesis of epoxyphosphonates
专利号:WO-2016178162-A1 优先权日:2015-05-05 标题 :Synthesis of intermediates used in the manufacture of anti-hiv agents
专利号:US-5350696-A 优先权日:1993-04-13 标 题:2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines
专利号:RU-2097384-C1 优先权日:1989-10-31 标题 :Derivatives of amino-7-(chr2r3)-3h,5h-pyrrolo-[3,2-d]-pyrimidine-4-one, methods of their synthesis and a method of selective inhibition of mammalian t-lymphocytes proliferation and no effecting on chr2r3-lymphocytes