CAS: 23229-26-7; 2,5-Dibromopyrazine

相似化合物

56423-63-3 23229-25-6 95538-03-7

上下游产品

CAS号59489-71-3 2-氨基-5-溴吡嗪 | CAS号290-37-9 吡嗪 | CAS号56423-63-3 2-溴吡嗪 | CAS号13051-89-3 吡嗪-2,5-二羧酸二甲酯 | CAS号1049026-49-4 2-溴-5-甲硫基吡嗪 | CAS号86942-29-2 2,5-bis(methyls... | CAS号955050-06-3 2-Bromo-5-(4-me... | CAS号955050-08-5 4-(5-溴-2-吡嗪)吗啉 | CAS号446286-90-4 2-溴-5-(哌嗪-1-基)吡嗪 | CAS号5398-63-0 Pyrazine, 2,5-d... | CAS号58861-90-8 2-methyl-5-phen...

2-氨基-5-溴吡嗪置于氢溴酸,溴,Sodium Nitrite体系中,化学反应生成2,5-二溴吡嗪
参考文献:具有末端da基团的线性和角吡嗪基结构异构体的结构性质关系及其光物理性质的评价
标题:具有末端da基团的线性和角吡嗪基结构异构体的结构性质关系及其光物理性质的评价
摘要:通过sonogashira反应合成了一系列基于吡嗪的线性和角形推挽生色团,并通过x射线分析对其进行了进一步研究.通过实验和量子化学方法对光物理性质进行了全面的研究.建立了电子给体和受体对线性和有角度支架的吸收和发射光谱的剧烈影响.量子化学计算为观测到的光谱特征提供了可靠的理论合理性.这些结果表明,沿线性方向扩展吡嗪受体的共轭可显着改善分子内电荷转移相互作用.
Doi:10.1016/j.Dyepig.2019.04.057

专利信息

专利号:US-10253004-B2
优先权日:2017-01-26
标 题:Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
发明人：ECKHARDT MATTHIAS; WAGNER HOLGER; PETERS STEFAN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of formula I, n nwherein the groups R, R 1 , R 2 , R 3 , m and n are defined herein, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-2019152962-A1
优先权日:2016-07-14
标题 :Cyclopropyl derivatives as ror-gamma modulators
发明人：DESAI RANJIT; KUMAR SANJAY S; PANDYA VRAJESH; DESAI JIGAR; RAVAL SAURIN
权利人:CADILA HEALTHCARE LTD
摘要:The present invention provides compounds which are modulators of RORγ and their use for the treatment of diseases or conditions mediated by RORγ. Further, the present invention relates to processes of preparing such compounds, their tautomeric forms, novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, methods for using such compounds and pharmaceutical compositions containing them (Formula I).

专利号:WO-2024068976-A1
优先权日:2022-09-29
标 题 :Azole derivatives as shp2 inhibitors
发明人：PETROCCHI ALESSIA; MONTALBETTI CHRISTIAN; DI FABIO ROMANO; CIAMMAICHELLA ALINA; ROSSETTI ILARIA
权利人:IRBM S P A; C N C C S S C A R L COLLEZIONE NAZ DEI COMPOSTI CHIMICI E CENTRO SCREENING
摘要:The present invention relates to new compounds capable of inhibiting the activity of SHP2 phosphatase. Compounds of the invention can be used for the treatment of disorders associated with SHP2 deregulation. The present invention also relates to pharmaceutical compositions containing said compounds and to their method of synthesis.

专利号:CN-215783219-U
优先权日:2021-06-09
标题 :A kind of intermediate raw material 2,5-dibromopyrazine synthesis feeding device

专利号:CN-112300057-B
优先权日:2020-10-19
标 题 :A kind of D-A-D hole transport material and its synthesis method and application