CAS: 15912-75-1; N-Propyltriphenylphosphonium Bromide

该化合物是化学公式\(C21}H22}PCl-\)的四磷盐,该化合物在有机合成中广泛用作分阶段转移催化剂(PTC),因为它能够促进不同阶段之间的反应,其稳定的磷化能增强核生殖替代和其他转化的再活性.该物质链有助于有机和水介质中的中度溶性,使其能适用于多种系统.此外,其晶体固体形式确保了处理和储存的便利.该化合物在工业和实验室环境中特别受到重视,因为它在保持高选择性和高产量的同时,在加速反应方面效率.

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6228-47-3 14350-50-6 13371-17-0

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号4252-88-4 [phenyl(propyl)...

合成工艺路线路线简述

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    专利信息


    专利号:WO-9955664-A1
    优先权日:1998-04-24
    标 题 :Preparation of carbocyclic compounds
    发明人:BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
    权利人:GILEAD SCIENCES INC; BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
    摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

    专利号:US-6518438-B2
    优先权日:1996-08-23
    标题:Preparation of cyclohexene carboxylate derivatives
    发明人:KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
    权利人:GILEAD SCIENCES INC
    摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

    专利号:US-5886213-A
    优先权日:1997-08-22
    标题:Preparation of carbocyclic compounds
    发明人:KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
    权利人:GILEAD SCIENCES INC
    摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

    专利号:US-6204398-B1
    优先权日:1996-08-23
    标题 :Preparation of cyclohexene carboxylate derivatives
    发明人:KENT KENNETH M; KIM CHOUNG U; MCGEE LAWRENCE R; MUNGER JOHN D; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; KELLY DAPHNE E; WILLIAMS MATTHEW A; ZHANG LIJUN
    权利人:GILEAD SCIENCES INC
    摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates such as those having formulas (I)-(IV), useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

    专利号:US-9580547-B2
    优先权日:2011-11-04
    标 题 :Catalysts and methods for polymer synthesis
    发明人:ALLEN SCOTT D; JOB GABRIEL; FARMER JAY J
    权利人:NOVOMER INC
    摘要:The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

    专利号:US-7807837-B2
    优先权日:2004-05-07
    标 题 :Scalable synthesis of imidazole derivatives
    发明人:JONES TODD K; MANI NEELAKANDHA
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:Imidazole derivatives, compositions containing them, methods of preparing them, including regioselective scale-up synthetic methods, and methods of using them.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:The Rational Design Of Modified Cinchona Alkaloid Catalysts. Application To A New Asymmetric Synthesis Of Chiral Chromanes
    作者:Alain Merschaert,Pieter Delbeke,Désiré Daloze,Georges Dive |发布日期:2004.6
    摘要:Step Is The Intramolecular Conjugate Addition Of A Phenolic Nucleophile On A α,β-Unsaturated Ester Catalyzed By Cinchona Alkaloids. The High Ee'S Obtained With Cinchonine And Its Derivatives Have Been Rationalized By Ab Initio Quantum Chemistry Calculations Of Transition State Structures.

    合成参考文献


    摘要:Schobert, R.; Gordon, G. J., Science of Synthesis, (2004) 27, 1023.
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