CAS: 15894-04-9; 4-Fluorobenzylmercaptan

该化合物是一种有机硫化合物,其特征是附于苯环的硫醇(-SH)组,该组在副位置上还带有氟替代物.该化合物一般是无色的,可粉色的黄色液体,有独特的气味.它溶于有机溶剂中,并且由于芳香环的疏水性,水溶性有限.氟原子的存在可能影响化合物的再活动性和极性,有可能增强它的电极性.4-氟苯并苯乙乙醇在各种化学应用中都有意义,包括作为有机合成和药物开发中的建筑块.安全考虑包括谨慎地处理它,因为其潜在毒性和刺激性.在冷,干燥的地方适当储存,远离不相容的材料,对于保持其稳定性和防止降解至关重要.

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72364-46-6 459-46-1 5925-85-9

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CAS号98-16-8 间三氟甲苯胺 | CAS号459-46-1 对氟溴苄 | CAS号352-11-4 对氟氯苄 | CAS号459-56-3 对氟苯甲醇 | CAS号79-46-9 2-硝基丙烷 | CAS号75663-55-7 4-(2-fluorophen...

合成工艺路线路线简述

    📜间氨基三氟甲苯置于盐酸,Sodium Nitrite,Potassium Ethyl Xanthogenate,氢氧化钾体系中,用 水 用作溶剂,化学反应 0.5H,反应生成4-氟苄基硫醇
    参考文献:Ep1731506
    标题:Ep1731506

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    专利信息


    专利号:US-12180228-B2
    优先权日:2019-06-05
    标题:Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
    发明人：MOVASSAGHI MOHAMMAD; OLSSON CHASE ROBERT; SCOTT TONY Z; CHEAH JAIME; PAYETTE JOSHUA NATHANIEL
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:The present disclosure provides, e.g., compounds, compositions, kits, methods of synthesis, and methods of use, involving epipolythiodiketopiperazines and polythiodiketopiperazines.

    专利号:US-7256177-B2
    优先权日:2003-06-17
    标题 :Lincomycin derivatives possessing antibacterial activity
    发明人：LEWIS JASON G; ANANDAN SAMPATH K; O'DOWD HARDWIN; GORDEEV MIKHAIL F
    权利人:VICURON PHARM INC
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

    专利号:US-7361743-B2
    优先权日:2004-02-11
    标 题 :Lincomycin derivatives possessing antibacterial activity
    发明人：LEWIS JASON G; ANANDAN SAMPATH K; O'DOWD HARDWIN; GORDEEV MIKHAIL F; LI LIANSHENG
    权利人:PFIZER
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

    专利号:US-7199106-B2
    优先权日:2003-06-17
    标题 :Lincomycin derivatives possessing antimicrobial activity
    发明人：LEWIS JASON G; ANANDAN SAMPATH-KUMAR; O'DOWD HARDWIN; GORDEEV MIKHAIL F
    权利人:VICURON PHARM INC
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

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    合成参考文献


    摘要:Tang, R.-Y., Science of Synthesis: Knowledge Updates, (2024) 1, 425.
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