专利号:US-6965034-B2 优先权日:1996-12-03 标题:Synthesis of epothilones, intermediates thereto and analogues thereof 发明人:DANISHEFSKY SAMUEL J; BERTINATO PETER; SU DAI-SHI; MENG DONGFANG; CHOU TING-CHAO; KAMENECKA TED; SORENSEN ERIK J; BALOG AARON; SAVIN KENNETH A; KUDUK SCOTT; HARRIS CHRISTINA; ZHANG XIU-GUO; BERTINO JOSEPH R 权利人:SLOAN KETTERING INST CANCER 摘要:The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilones.
专利号:US-6204388-B1 优先权日:1996-12-03 标 题:Synthesis of epothilones, intermediates thereto and analogues thereof
专利号:EP-1058679-A4 优先权日:1998-02-25 标题 :SYNTHESIS OF EPOTHILONES, THEIR INTERMEDIATES AND THEIR ANALOGS
专利号:US-6603023-B2 优先权日:1996-12-03 标 题:Synthesis of epothilones, intermediates thereto and analogues thereof
专利号:WO-9943653-A1 优先权日:1998-02-25 标 题:Synthesis of epothilones, intermediates thereto and analogues therof
专利号:US-6316630-B1 优先权日:1996-12-03 标 题:Synthesis of epothilones, intermediates thereto and analogues thereof