CAS: 913835-32-2; 5-Borono-2-Chlorobenzoic Acid

该化合物是有机合成中的一种有价值的试剂,以其高纯度和稳定性而著称,其独特的boronic酸和氯化替代成分为创造多种有机化合物提供了多种用途.该化合物适合于制造具有定制特性的多功能分子,使其成为药物发现和材料科学研究中不可或缺的基石.

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CAS号355142-36-8 2-氯-5-(5-甲酰基呋喃-...

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  • 54932-72-8 = 913835-32-2
    反应条件:1.1 Reagents: Triisopropyl Borate Solvents: Tetrahydrofuran; Rt -> -78 °C; -78 °C; 30 Min,-78 °C; 2 H,-78 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 62.1 Reagents: Sodium Hydroxide,Tetrabutylammonium Bromide,Permanganic Acid (Hmno4),Potassium Salt (1:1) Solvents: Water; 4 H,Rt2.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 2,Rt
    标题:Optimization Of Synthesis Process Of (4-Chloro-3-Carboxylphenyl) Boronic Acid
    作者:Teng,Minggang; Et Al
    参考文献:Guangdong Huagong 日期:2015 卷标:42(3) 页码:30-31]

    161950-10-3 = 913835-32-2
    反应条件:1.1 Reagents: Sodium Hydroxide,Tetrabutylammonium Bromide,Permanganic Acid (Hmno4),Potassium Salt (1:1) Solvents: Water; 4 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 2,Rt
    标题:Optimization Of Synthesis Process Of (4-Chloro-3-Carboxylphenyl) Boronic Acid
    作者:Teng,Minggang; Et Al
    参考文献:Guangdong Huagong 日期:2015 卷标:42(3) 页码:30-31

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专利信息


专利号:US-11299484-B2
优先权日:2018-10-10
标 题 :Inhibiting fatty acid synthase (FASN)
发明人：MARTIN MATTHEW W; ZABLOCKI MARY-MARGARET; MENTE SCOT; DINSMORE CHRISTOPHER; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:FORMA THERAPEUTICS INC
摘要:The present disclosure is directed to inhibitors of FASN. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of FASN. For instance, the disclosure is concerned with compounds and compositions for inhibition of FASN, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of FASN, and methods of synthesis of these compounds.

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