CAS: 605-62-9; 4-Nitronaphthalen-1-Ol

相似化合物

5959-56-8 4900-63-4 77542-54-2

上下游产品

CAS号86-57-7 1-硝基萘 | CAS号90-15-3 1-萘酚 | CAS号776-34-1 4-硝基-1-萘胺 | CAS号4900-63-4 1-甲氧基-4-硝基萘 | CAS号321-38-0 1-氟萘 | CAS号605-61-8 1-氯-4-硝基萘 | CAS号341-92-4 1-氟-4-硝基萘 | CAS号6549-14-0 4-nitro-1-napht... | CAS号134-32-7 1-萘胺 | CAS号4965-30-4 1,4-Naphthalene... | CAS号109392-88-3 1-(4-nitronapht... | CAS号605-69-6 马休黄 | CAS号4900-63-4 1-甲氧基-4-硝基萘 | CAS号2834-90-4 4-氨基-1-萘酚 | CAS号776-34-1 4-硝基-1-萘胺 | CAS号285983-48-4 多马莫德 | CAS号1283526-53-3 1-[1-(4-Methylp... | CAS号103769-08-0 N-[2-(4-nitrona... | CAS号317806-88-5 4-[2-(4-NITRONA... | CAS号37025-38-0 4-[(7-chloroqui...

1-氨基-4-硝基萘置于sodium Hydroxide体系中,化学反应 5.0H,以89%的收率获得产物4-硝基-1-萘酚
参考文献:Antimalarial Drugs. 61. Synthesis And Antimalarial Effects Of 4-[(7-Chloro-4-Quinolinyl)Amino]-2-[(Diethylamino)Methyl]-6-Alkylphenols And Their N.Omega.-Oxides
标题:Antimalarial Drugs. 61. Synthesis And Antimalarial Effects Of 4-[(7-Chloro-4-Quinolinyl)Amino]-2-[(Diethylamino)Methyl]-6-Alkylphenols And Their N.Omega.-Oxides
摘要:A Series Of 4-[(7-Chloro-4-Quinolinyl)Amino]-2-[(Diethylamino)Methyl]-6-Alkylphenols And Their N Omega-Oxides Were Synthesized By The Condensation Of 4,7-Dichloroquinoline And 4,7-Dichloroquinoline N Omega-Oxide With Appropriately Substituted 4-Amino-2-[(Diethylamino)Methyl]-6-Alkylphenol Dihydrochlorides. The Latter Precursors Were Prepared In A Six-Step Synthesis Starting From Available 2-Alkylphenols. Several Of The Title Compounds Display Potent Antimalarial Activity In Mice.
DOI:10.1021/jm00388A027

专利信息

专利号:US-6894173-B2
优先权日:1999-07-09
标 题 :Intermediates useful for synthesis of heteroaryl-substituted urea compounds, and processes of making same
发明人：ZHANG LIN-HUA; ZHU LEI
权利人:BOEHRINGER INGELHEIM PHARMA
摘要:Disclosed are novel processes and novel intermediate compounds for preparing aryl-and heteroaryl-substituted urea compounds of the formula(I) wherein Ar 1 , Ar 2 , L, Q and X are described herein. The product compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases.

专利号:US-2003166931-A1
优先权日:1999-07-09
标 题 :Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents

专利号:US-2003166930-A1
优先权日:1999-07-09
标题 :Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents

专利号:US-2003181718-A1
优先权日:1999-07-09
标 题 :Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents

专利号:EP-1200411-B1
优先权日:1999-07-09
标题:Process for synthesis of heteroaryl-substituted urea compounds

专利号:EP-1200411-A2
优先权日:1999-07-09
标题:Novel process for synthesis of heteroaryl-substituted urea compounds