CAS: 5779-94-2; 2,5-Dimethylbenzaldehyde

上下游产品

formaldehyd 2,5-dimethylbenzyl chloride hydrogen cyanide para-xylene 3-(2,5-dimethylphenyl)propenoic acid 2,5-dimethylbenzyl alcohol 3,6-dimethyl-2-nitro-benzaldehyde bis-(2,5-dimethyl-benzylidene)-hydrazine

2,5-二甲基苯甲醇置于2,2,6,6-四甲基哌啶氧化物体系中,用 乙醇 作为反应溶剂,化学反应 18.0H,以63%的收率获得产物2,5-二甲基苯甲醛
参考文献:Cui-y沸石/ Tempo在乙醇中催化氧化苄醇的绿色方法,无需其他添加剂
标题:Cui-y沸石/ Tempo在乙醇中催化氧化苄醇的绿色方法,无需其他添加剂
摘要:使用tempo(tempo = 2,2,6,6-四甲基-1-哌啶-N-氧基)作为自由基助催化剂的cu I-Y沸石催化剂,对乙醇中的苄醇进行有氧氧化的高效和绿色方案据报道在温和条件下存在大气.通过cucl和hy沸石之间的离子交换制备的cu I-Y沸石已通过多种光谱技术(包括xrd,Xps,Sem,Edx和hrtem)进行了全面表征.铜的引入(我)进入3D沸石骨架,使催化剂具有非常好的耐久性.重复运行的结果表明,在前三个运行中,活性几乎没有下降,此后观测到产率有更大幅度的下降,而选择性几乎保持不变.活性降低归因于催化过程中cuo的形成和铜向液相的漂白,其中cuo的形成被认为是主要的起因,因为每次运行的漂白损失可以忽略不计(<2 %).在该催化体系中,除tempo外,不需要其他添加剂,无论是碱还是配体,这在某些已报道的醇氧化催化体系中都是必不可少的.有氧氧化在温和的条件下(60°C,18小时)
DOI:10.1039/d0Nj03776A

专利信息

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-5175302-A
优先权日:1987-07-13
标 题 :Nucleophilic fluoroalkylation of aldehydes
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:US-4837327-A
优先权日:1987-07-13
标 题 :Process for nucleophilic fluoroalkylation of aldehydes
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to alkehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:US-4999429-A
优先权日:1989-01-09
标 题 :Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:WO-9710221-A1
优先权日:1995-09-15
标 题:Synthesis of quinazolinone libraries
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TORREY PINES INST
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-2005250765-A1
优先权日:2000-08-16
标题 :Diazepinones as antiviral agents
发明人：CHO HIDETSURA; GOGLIOTTI ROCCO D; HAMILTON HARRIET W; KRASUTSKY ALEXEI; NAKAMURA TAKESHI; TADA HIROKI; WEBER PETER C
权利人:CHO HIDETSURA; GOGLIOTTI ROCCO D; HAMILTON HARRIET W; KRASUTSKY ALEXEI; NAKAMURA TAKESHI; TADA HIROKI; WEBER PETER C
摘要:The invention is novel compounds of formula n nwhich exhibit an improved therapeutic index and improved metabolic stability which are useful in the treatment and/or prevention of herpes viral infections. Novel intermediates useful in the synthesis of the final compounds are also part of the invention.