CAS: 42242-11-5; 3-Amino-2-Pyridinecarbonitrile

该化合物是一个有机化合物,其特点是其环形结构,由六人组成,含有一个氮原子的芳香环;该化合物的特点是氨基氨基化合物(-NH2)和一个配有丙烯酸环的丙烯基化合物组(-CN),具体在3和2个位置上;这些功能组的存在具有不同的化学特性,例如由于氨基氨基化合物组而参与氢联产的能力,以及由于西诺组的电子抽取性质而具有的核生殖反应潜力.3-Amino-2-pyridrictrile在室温时通常是固的,在极溶剂中可能表现出中性溶性.由于药化学和材料科学在合成药物和农用化学品方面的潜在应用,这些功能组具有不同领域的利益,例如,由于许多含氮的乙型循环,它也可能展示生物活动,使其成为药物研究的主体.

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CAS号6298-19-7 2-氯-3-氨基吡啶 | CAS号557-21-1 氰化锌 | CAS号39856-58-1 2-溴-3-氨基吡啶 | CAS号6332-56-5 2-羟基-3-硝基吡啶 | CAS号19755-53-4 2-溴-3-硝基吡啶 | CAS号50608-99-6 3-氨基吡啶-2-甲酰胺

合成工艺路线路线简述

    📜2-溴-3-氨基吡啶置于cucn体系中,化学反应生成 3-氨基-2-氰基吡啶
    参考文献:Berrie Et Al.,Journal Of The Chemical Society,1952,P. 2042,2044
    标题:Berrie Et Al.,Journal Of The Chemical Society,1952,P. 2042,2044

    海关参考信息

    专利信息


    专利号:US-3950160-A
    优先权日:1972-09-27
    标题:Inhibiting the growth of weeds with 2-substituted pyrdidopyimidines and salts thereof
    发明人:ABU EL-HAJ MARWAN J; DOMINY BERYL WILLIAM
    权利人:PFIZER
    摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.

    专利号:US-3962264-A
    优先权日:1972-09-27
    标 题:Process for making 2-amino nicotinonitrile
    发明人:ABU EL-HAJ MARWAN J; DOMINY BERYL WILLIAM
    权利人:PFIZER
    摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.

    专利号:US-3917624-A
    优先权日:1972-09-27
    标题:Process for producing 2-amino-nicotinonitrile intermediates
    发明人:ABU EL-HAJ MARWAN J; DOMINY BERYL WILLIAM
    权利人:PFIZER
    摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.

    专利号:US-3862191-A
    优先权日:1972-09-27
    标 题 :Pyrido{8 2,3-d{9 pyrimidin-4(3H)-one
    发明人:EL-HAJ MARWAN J ABU; DOMINY BERYL WILLIAM
    权利人:PFIZER
    摘要:2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.

    专利号:US-9695191-B2
    优先权日:2009-08-05
    标题 :Conformationally constrained, fully synthetic macrocyclic compounds
    发明人:OBRECHT DANIEL; ERMERT PHILIPP; OUMOUCH SAID; LACH FRANCK; LUTHER ANATOL; MARX KARSTEN; MÖHLE KERSTIN
    权利人:OBRECHT DANIEL; ERMERT PHILIPP; OUMOUCH SAID; LACH FRANCK; LUTHER ANATOL; MARX KARSTEN; MÖHLE KERSTIN; POLYPHOR AG
    摘要:Conformationally restricted, spatially defined 12-30 membered macrocyclic ring systems of type (I) are constituted by three distinct building blocks: an aromatic template a, a conformation modulator b and a spacer moiety c as detailed in the description and the claims. Macrocycles of type (I) are readily manufactured by parallel synthesis or combinatorial chemistry. They are designed to interact with specific biological targets. In particular, they show agonistic or antagonistic activity on the motilin receptor (MR receptor), on the serotonin receptor of subtype 5-HT 2B (5-HT 2B receptor), and on the prostaglandin F2•receptor (FP receptor). They are thus potentially useful for the treatment of hypomotility disorders of the gastrointestinal tract such as diabetic gastroparesis and constipation type irritable bowl syndrome; of CNS related diseases like migraine, schizophrenia, psychosis or depression; of ocular hypertension such as associated with glaucoma and preterm labour.

    专利号:CN-116444527-A
    优先权日:2023-03-30
    标题 :A high-efficiency construction method of fused tricyclic skeleton and the synthesis method of its energetic derivatives

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s11224-023-02221-0
    摘要:Loganathan K, Anandan A, Purushothaman M, Jebaraj PD, Thanigaimani K, Percino MJ, Venkatesan P. Synthesis, crystal structure, Hirshfeld surface analysis, and DFT studies of 2-bromo-4,6-bis(dibromoacetyl)resorcinol. Struct Chem. 2023 Aug 19;35(2):627–40. doi: 10.1007/s11224-023-02221-0.
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