CAS: 4099-85-8; ((3Ar,4R,6R,6Ar)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4-D][1,3]Dioxol-4-yl)Methanol

相似化合物

4099-88-1 72402-14-3 645417-47-6

上下游产品

Methyl 5-O-(Tetrahydrofuran-2-yl)-(2,3-O-Methylethylidene)-β-D-Ribofuranoside 1236149-25-9
Methyl 5-O-(Tetrahydro-2H-Pyran-2-yl)-(2,3-O-Methylethylidene)-β-D-Ribofuranoside 1236149-23-7
2,3-异亚丙氧基-D-呋喃核糖苷 2,3-O-Isopropylidene-D-Ribofuranose 4099-88-1
2,3-O-Isopropylidene-β-D-Ribofuranose 67814-68-0
Methyl 5,6-Dideoxy-2,3-O-Isopropyliden-β-D-Ribo-Hex-5-Eno-Furanosid 29325-28-8
Methyl 5-Deoxy-5-Iodo-2,3-Isopropylidene-β-D-Ribofuranoside 38838-06-1
1-甲氧基-2,3-O-异亚丙基-5-苄氧基-Beta-D-呋喃核糖苷 (2R,3R,4R,5R)-2-Benzyloxymethyl-3,4-Isopropylidenedioxy-5-Methoxytetrahydrofuran 33019-63-5
(3Ar,4S,6R,6Ar)-Tetrahydro-6-Methoxy-2,2-Dimethylfuro-[3,4-D][1,3]Dioxole-4-Carbaldehyde 33985-40-9
Methyl 5-Bromo-5-Deoxy-2,3-O-Isopropylidene-β-D-Riboside 38838-05-0
Methyl 2,3-O-Isopropylidene-β-D-Ribofuranoside Methanesulfonate

卡培他滨杂质25置于硫酸,对甲苯磺酸体系中,化学反应 40.0H,反应生成 甲基-2,3-O-异亚丙基-Beta-D-呋喃核糖苷
参考文献:甲基2-O-烯丙基-(和3-O-烯丙基)-5-O-苄基-β-D-呋喃核糖苷的合成.
标题:甲基2-O-烯丙基-(和3-O-烯丙基)-5-O-苄基-β-D-呋喃核糖苷的合成.
摘要:将d-核糖转化为甲基5-O-苄基-β-D-呋喃呋喃糖苷,并且在锡介导的烯丙基化中,得到2-O-烯丙基和3-O-烯丙基衍生物的混合物,将其通过色谱法分离.通过3-O-烯丙基-5-O-苄基-1,2-O-异亚丙基-α-D-呋喃核糖转化后,更具极性的异构体被表征为3-O-烯丙基衍生物(也由3-O-烯丙基-1,2-:5,6-二-O-异亚丙基-α-D-呋喃糖)成已知的5-O-苄基-1,2-O-异亚丙基-α-D-呋喃核糖.通过甲基2-O-烯丙基-5-O将3-O-烯丙基-5-O-苄基-β-D-呋喃呋喃糖苷转化为甲基2-O-烯丙基-5-O-苄基-β-D-核呋喃糖苷-苄基-3-O-(丙-1-烯)-β-D-呋喃呋喃糖苷.
DOI:10.1016/0008-6215(95)00308-8

专利信息

专利号:WO-2013092900-A1
优先权日:2011-12-23
标 题 :Synthesis of triazolopyrimidine compounds