CAS: 2198-64-3; (S)-2-Benzamidopropanoic Acid

相似化合物

17966-60-8 1205-02-3 38767-73-6

上下游产品

CAS号98-88-4 苯甲酰氯 | CAS号302-72-7 DL-2-氨基丙酸 | CAS号7244-67-9 N-苯甲酰-L-丙氨酸甲酯 | CAS号582-61-6 benzoylazide | CAS号4774-76-9 N-benzoyl-alani... | CAS号64-17-5 乙醇 | CAS号4452-17-9 2-benzamidoprop... | CAS号100718-97-6 ethyl 4-benzami... | CAS号1462-81-3 Benzamide,N-[2-... | CAS号22260-83-9 4-甲基-2-苯基-1,3-噁... | CAS号18227-62-8 3-苯甲酰氨基丁酮 | CAS号338-69-2 D-丙氨酸 | CAS号65-85-0 苯甲酸 | CAS号56-41-7 L-丙氨酸 | CAS号17966-60-8 (R)-2-苯酰胺基丙酸 | CAS号2198-64-3 N-苯甲酰-L-丙氨酸 | CAS号24250-70-2 N-(1-carbamoyle...

📜番木鳖碱 反应生成N-苯甲酰-L-丙氨酸
参考文献:Pope; Gibson,Journal Of The Chemical Society,1912,Vol. 101,P. 940,942
标题:Pope; Gibson,Journal Of The Chemical Society,1912,Vol. 101,P. 940,942

专利信息

专利号:US-10676423-B2
优先权日:2017-02-21
标题 :Structure and synthesis of highly fluorinated amino acid derivatives
发明人：WEAVER JIMMIE DEAN; TEEGARDIN KIP ALLEN; ARORA AMANDEEP
权利人:UNIV OKLAHOMA STATE
摘要:Methods of synthesizing polyfluorinated amino acid derivatives are disclosed, along with polyfluorinated amino acid derivatives produced from said methods, as well as compositions containing same. The synthesis methods utilize an oxazolone and a perfluoroarene to produce the polyfluorinated amino acid derivatives.

专利号:US-2010273787-A1
优先权日:2007-11-15
标题:Kynurenine-aminotransferase inhibitors
发明人：SCHWARCZ ROBERT; KAJII YASUSHI; ONO SHIN-ICHIRO
权利人:SCHWARCZ ROBERT; KAJII YASUSHI; ONO SHIN-ICHIRO
摘要:Compounds of formula (I): prodrug derivatives and/or pharmaceutically acceptable salt thereof, selectively inhibit the enzyme kynurenine aminotransferase, thereby reducing the synthesis of kynurenic acid. The compounds are used for the treatment of psychiatric and neurological diseases which benefit from an increase in glutamatergic and/or cholinergic neurotransmission, such as schizophrenia, depression, bipolar illness, anxiety and Alzheimer's disease. Furthermore, the compounds of the invention are useful for stimulating attention, memory and other cognitive processes in normal individuals of any age, including children, adolescents and the elderly. Additionally, the compounds of the invention are also useful for treatment of patients suffering from malaria by preventing parasite gametogenesis and fertility based on reduction of xanthurenic acid formation from its bioprecursor 3-hydroxy kynurenine.

专利号:WO-2006013085-A1
优先权日:2004-08-06
标题 :4-sulfonyl-substituted benzoylalanine derivates useful as kynurenine-aminotransferase inhibitors
发明人：PELLICCIARI ROBERTO; SCHWARCZ ROBERT; GUIDETTI PAOLO
权利人:PELLICCIARI ROBERTO; SCHWARCZ ROBERT; GUIDETTI PAOLO
摘要:The invention relates to compounds of formula (I), in which R, R' and R' are as defined in the disclosure and the pharmaceutically acceptable esters thereof. The compounds of the invention reduce the synthesis of kynurenic acid thus inhibiting the enzyme kynurenine aminotransferase and can be used for the preparation of medicaments for the treatment of those psychiatric and neurological diseases which benefit from an increase in glutamatergic and/or cholinergic neurotransmission, such as depression, bipolar illness, anxiety, Alzheimer's disease. Furthemore, the compounds of the invention are useful for stimulating attention, memory and other cognitive processes in normal individuals of any age, including children, adolescents and the elderly.

专利号:US-2020123099-A1
优先权日:2017-02-21
标题 :Structure and Synthesis of Highly Fluorinated Amino Acid Derivatives

专利号:US-5514694-A
优先权日:1992-09-21
标题 :Peptidyl ketoamides
发明人：POWERS JAMES C; LI ZHAOZHAO; PATIL GIRISH S; CHU DER-LUN
权利人:GEORGIA TECH RES INST
摘要:A novel class of peptide alpha -ketoamides useful for selectively inhibiting serine proteases, selectively inhibiting cysteine proteases, generally inhibiting all serine proteases, and generally inhibiting all cysteine proteases, having the formula Y-CO-AA2-AA1-CO-NH-X. Processes for the synthesis of peptidyl alpha -ketoamide derivatives.

专利号:US-8518885-B2
优先权日:2008-02-06
标题 :Heterocyclic peptide ketoamides
发明人：POWERS JAMES C; GLASS JONATHAN D; OVAT ASLI; LI ZHAOZHAO
权利人:POWERS JAMES C; GLASS JONATHAN D; OVAT ASLI; LI ZHAOZHAO; GEORGIA TECH RES INST; UNIV EMORY
摘要:A novel class of peptide α-ketoamides useful for selectively inhibiting calpains, selectively inhibiting cysteine proteases, and generally inhibiting all cysteine proteases, having the formula M-AA 2 -AA 1 -CO—NH—(CH 2 ) n —R 3 . Processes for the synthesis of peptidyl α-ketoamide derivatives. Compositions and methods for inhibiting cysteine proteases, inhibiting calpains, and treating disease caused by cysteine proteases and calpains are provided.