CAS: 1955-26-6; Diphosphoric Acid-1-β-L-Rhamnopyranosyl Ester-2-Uridin-5'-Yl Ester

该化合物是一种核糖,它是含甘醇的甘醇糖的生物合成中的关键中间体,例如细菌细胞壁壁聚沙焦和植物二代代代谢物.这种化合物对于酶合成反应至关重要,它作为活性捐献者基质,用于伦诺基转移酶.它的高度纯度和稳定性使它成为生物化学和微生物研究的宝贵试剂,特别是在碳水化合物代谢学,病原体振荡和藻理学研究中. UDP-rhamnose被广泛用于酶实验,结构研究以及复合甘油合成,为研究人员提供一种可靠的工具,用于繁殖甘醇途径.

结构式图片

合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成[[(2R,3S,4R,5R)-5-(2,4-二氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-基]甲氧基-羟基磷酰][(2R,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢吡喃-2-基]磷酸氢酯
    参考文献:The Enzymic Synthesis Of Uridine Diphosphate L-Rhamnose
    标题:The Enzymic Synthesis Of Uridine Diphosphate L-Rhamnose
    摘要:
    Doi:10.1016/0006-291X(62)90264-4

    海关参考信息

    专利信息


    专利号:US-2024132927-A1
    优先权日:2020-12-02
    标 题 :Modular glycan production with immobilized bionanocatalysts
    发明人:CORGIE STEPHANE CEDRIC; HOEPKER ALEXANDER CHRIS
    权利人:ZYMTRONIX CATALYTIC SYSTEMS INC
    摘要:The invention provides modular cell-free de-novo synthesis of glycans with immobilized bionanocatalysts. The invention provides materials, and in particular, magnetic materials, for producing glycans of defined length and sequences using one or more enzymes that are immobilized within bionanocatalysts (BNCs) which in turn are embedded within scaffolds to control the synthesis in batch or continuous processes manufacturing. In some embodiments, the scaffolds are high magnetism and high porosity composite blends of thermoplastics or thermosets comprising magnetic particles that form powders. In some embodiments, Selective Laser Sintering (SLS) is used to design and produce objects via 3D printing by sintering composite magnetic powders. The modular flow cells may be mixed and matched for a highly customizable and highly efficient cell-free manufacturing process. In some embodiments the elementary and system modules provided by the invention are employed. In preferred embodiments, human milk oligosaccharides (HMOs) are produced.

    专利号:US-2018237819-A1
    优先权日:2011-11-23
    标 题 :Methods and Materials for Enzymatic Synthesis of Mogroside Compounds

    专利号:CN-105647998-A
    优先权日:2016-03-22
    标题 :Application of Arabidopsis thaliana Glycosyltransferase UGT79B2 in Catalytic Synthesis of Anthocyanin Rhamnoside

    专利号:US-2015225758-A1
    优先权日:2011-11-08
    标 题 :Genetically modified cells and methods for making activated sugar-nucleotides
    发明人:BAR-PELED MAOR; YANG TING
    权利人:UNIV GEORGIA
    摘要:This disclosure generally relates to genetically engineered cells and methods of making and using such genetically engineered cells. Generally, the genetically engineered cells exhibit an increase in synthesis of an activated sugar-nucleotide compared to a wild type control. In some embodiments, the activated sugar-nucleotide produced by the genetically engineered cell is an activated sugar-nucleotide that is not natively synthesized by wild type, un-engineered cell. In some embodiments, the activated sugar-nucleotide is an activated uridine diphosphate sugar nucleotide. In other embodiments, the activated sugar-nucleotide is an activated cysteine monophosphate sugar nucleotide. In still other embodiments, the activated sugar-nucleotide is an activated guanosine diphosphate sugar nucleotide. In some embodiments, the activated sugar-nucleotide includes an isotopic label.

    专利号:CN-118272337-A
    优先权日:2024-04-11
    标题 :Three UDP-glycosyltransferases and application thereof in synthesis of oleanolic acid glycoside compound

    专利号:CN-114350646-B
    优先权日:2021-12-22
    标 题:UDP-sugar epimerase PsUGE2 and application thereof in synthesis of arabinoside
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    合成参考文献


    参考文献:10.1002/pro.3928
    摘要:Bockhaus NJ, Ferek JD, Thoden JB, Holden HM. The high‐resolution structure of a UDP‐L‐rhamnose synthase from Acanthamoeba polyphagaMimivirus. Protein Science. 2020 Oct;29(11):2164–74. doi: 10.1002/pro.3928.
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