CAS: 16766-30-6; 4-Chloroguaiacol

相似化合物

3743-23-5 16766-27-1 72403-03-3

上下游产品

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木榴油置于盐酸,氧气,Copper Dichloride体系中,用 水 用作溶剂,化学反应 0.33H,反应生成4-氯-2-甲氧基苯酚
参考文献:微波辐照下氯酚的高选择性合成
标题:微波辐照下氯酚的高选择性合成
摘要:在微波照射下,各种酚类的氧氯化反应在60分钟内完成,效率高,选择性好.这些反应采用氯化铜(II)(cucl2)作为催化剂,盐酸作为氯源,而不是昂贵且有毒的反应.在邻位和间位被给电子基团(甲基,甲氧基,异丙基等)取代的苯酚的氧氯化反应具有更高的转化率,更短的反应时间和出色的选择性.推导了提出的反应机理;一个电子从 Cucl2 转移到苯酚,随后形成互变异构自由基,该自由基可以被氯原子迅速捕获并转化为对位取代产物.
Doi:10.1155/2016/2960414

专利信息

专利号:US-6133483-A
优先权日:1998-07-30
标题 :Process for the production of 2,4,4'-trichloro-2'-methoxydiphenyl ether
发明人：CLEARY THOMAS F
摘要:A process is disclosed for the synthesis of 2,4,4'-trichloro-2'-methoxydiphenyl ether, and it's precursor 2,4,4'-trichloro-2'-bromodiphenyl ether, a novel compound.

专利号:US-7968752-B2
优先权日:2003-06-16
标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-2025026766-A1
优先权日:2022-01-12
标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors
发明人：LI JING; XU WENQING; WANG ZHIWEI
权利人:BEIGENE LTD
摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.

专利号:US-9926293-B2
优先权日:2014-05-30
标题 :Multivalent RAS binding compounds
发明人：STOCKWELL BRENT R; WELSCH MATTHEW
权利人:UNIV COLUMBIA
摘要:The present invention provides, inter alia, compounds having the structure: n nwherein R 7 , R 8 and n are as disclosed herein, that selectively bind a RAS protein at two or more sites and methods for their synthesis. Compositions and kits containing the compounds, as well as methods of using the compounds and compositions for ameliorating or treating the effects of a disease associated with altered RAS signaling, such as a cancer, in a subject and methods for effecting cancer cell death are also provided herein. Methods of identifying a multivalent compound which binds selectively to a target protein also are provided herein.

专利号:CN-113666812-A
优先权日:2021-09-10
标题 :Synthesis method of 5-halogenated veratraldehyde

专利号:CN-113666812-B
优先权日:2021-09-10
标 题 :Synthesis method of 5-halogenated veratraldehyde