CAS: 120444-71-5; N,N-Dimethyl-2-(((1R,2S,4R)-1,7,7-Trimethyl-2-Phenylbicyclo[2.2.1]Heptan-2-yl)Oxy)Ethan-1-Amine

📜(-)-2-Phenylisoborneol,2-氯-N,N-二甲基乙胺置于氨基钠体系中,用 1,4-二氧六环 用作溶剂,化学反应 6.5H,反应生成德伦环烷
参考文献:High Purity (1R,2S,4R)-(-)-2-[(2'-{n,N-Dimethylamino}-Ethoxy)]-2-[phenyl]-1,7,7-Tri-[methyl]-Bicyclo[2.2.1]Heptane And Pharmaceutically Acceptable Acid Addition Salts Thereof
标题:High Purity (1R,2S,4R)-(-)-2-[(2'-{n,N-Dimethylamino}-Ethoxy)]-2-[phenyl]-1,7,7-Tri-[methyl]-Bicyclo[2.2.1]Heptane And Pharmaceutically Acceptable Acid Addition Salts Thereof
摘要:该发明涉及高纯度的(1R,2S,4R)-(−)-2-[(2'-N,N-二甲基氨基乙氧基)]-2-[苯基]-1,7,7-三[甲基]-双环[2.2.1]庚烷及其药用可接受的酸盐,其含有不超过0.2%的(1R,3S,4R)-3-[(2'-N,N-二甲基氨基乙基)]-1,7,7-三[甲基]-双环[2.2.1]庚烷-2-酮和/或其药用可接受的酸盐.此外,该发明涉及制备这些化合物的方法.此外,该发明涉及含有1种或多种这些化合物的药物及其用途.

专利信息

专利号:US-9315483-B2
优先权日:2007-09-13
标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
发明人：JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
权利人:CONCERT PHARMACEUTICALS INC
摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

专利号:WO-2009035652-A1
优先权日:2007-09-13
标 题 :Synthesis of deuterated catechols and benzo[d][1,3] dioxoles and derivatives thereof

专利号:US-2023271983-A1
优先权日:2020-07-29
标题 :Functionalized isonitriles and products, preparation and uses thereof
发明人：SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
权利人:UNIV SANTIAGO COMPOSTELA
摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

专利号:US-2014336387-A1
优先权日:2007-09-13
标题:Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof

专利号:CA-2698808-A1
优先权日:2007-09-13
标题:Synthesis of deuterated catechols and benzo[d][1,3] dioxoles and derivatives thereof

专利号:EP-2200997-A1
优先权日:2007-09-13
标 题:Synthesis of deuterated catechols and benzoýd¨ý1,3¨dioxoles and derivatives thereof