CAS: 1048925-02-5; 5-Methyl-3-Nitro-1H-Pyrazole

相似化合物

31230-17-8 1204246-72-9 26621-44-3

上下游产品

3-methyl-5-aminopyrazole 1-amino-3-nitro-5-methylpyrazole 2-(5-methyl-3-nitro-1H-pyrazol-1-yl)ethanol

📜3-甲基吡唑置于硝酸乙酸酐,溶剂黄146,Sodium Carbonate体系中,用 水,四氯乙烯 用作溶剂,化学反应 23.0H,以72%的收率获得5-甲基-3-硝基-1H-吡唑
参考文献: Compounds,Compositions And Methods For Control Of Hepatitis C Viral Infections[fr] Composés,Compositions Et Procédés Pour Le Contrôle D'Infections Virales Par L'Hépatite C
标题: Compounds,Compositions And Methods For Control Of Hepatitis C Viral Infections[fr] Composés,Compositions Et Procédés Pour Le Contrôle D'Infections Virales Par L'Hépatite C
摘要:本发明涉及各种四氢吡唑并[1,5-A]嘧啶化合物,组合物,制备方法以及用于预防和治疗hcv感染及相关疾病的方法.该发明还涉及用于识别对四氢吡唑并[1,5-A]嘧啶化合物具有抗药性的hcv菌株的生物标志物.

专利信息

专利号:US-9575067-B2
优先权日:2007-05-23
标 题 :Polymeric carriers for immunohistochemistry and in situ hybridization
发明人：KOSMEDER II JERRY W; KERNAG CASEY A; JOHNSON DONALD; BIENIARZ CHRISTOPHER
权利人:VENTANA MED SYST INC
摘要:Certain disclosed embodiments of the present invention concern the synthesis, derivatization, conjugation to immunoglobulins and signal amplification based on discrete, relatively short polymers having plural reactive functional groups that react with plural molecules of interest. Reactive functional groups, such as hydrazides, may be derivatized with a variety of detectable labels, particularly haptens. The remaining reactive functional groups may be conjugated directly to a specific binding molecule, such as to the oxidized carbohydrate of the Fc region of the antibody. Disclosed conjugates display large signal amplification as compared to those based on molecules derivatized with single haptens, and are useful for assay methods, particularly multiplexed assays.