CAS: 6921-28-4; Dipropargylamine

相似化合物

262418-92-8 35161-71-8 93282-90-7

上下游产品

propargyl bromide 2-propynyl chloride Propargylamine di-prop-2-ynyl-carbamic acid tert-butyl ester2-(Di-prop-2-ynyl-amino)-ethanethiol 1,2-propanediene penta-3,4-dien-1-yne trans-prop-2-ynylideneamine

📜N-Boc-二炔丙胺置于三氟乙酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.0H,以99%的收率获得产物二炔丙胺
参考文献:设计为铜绿假单胞菌抗菌膜剂的柱[5]芳烃基聚阳离子糖[2]轮烷
标题:设计为铜绿假单胞菌抗菌膜剂的柱[5]芳烃基聚阳离子糖[2]轮烷
摘要:铜绿假单胞菌(Pa) 是一种人类病原体,属于发现新治疗方案的重中之重.它产生生物膜的倾向使治愈 Pa 感染所需的治疗变得非常复杂.在此,我们描述了一系列由中心半乳糖基化柱 [5] 芳烃,四岩藻糖基化树突和四胍亚基组成的新型轮烷的合成.除了最终的糖轮烷对两种 Pa 凝集素 Leca 和 Lecb 的高亲和力外,还证明了生物膜生长的有效抑制水平,表明它们的三个亚基协同工作.使用双 δ Leca δ Lecb的抗生物膜测定与野生型相比,突变体表明最好的糖轮烷的抗生物膜活性是凝集素介导的.文献中很少达到这种抗生物膜效力.重要的是,最终的轮烷都不是杀菌剂,这表明它们的抗生物膜活性不依赖于细菌杀灭,这是抗生物膜剂的一个罕见特征.
DOI:10.1021/acs.Jmedchem.1C01241

专利信息

专利号:US-2023322661-A1
优先权日:2020-08-21
标题 :Synthesis of N,N-Branched Sulfamoyl Fluoride Compounds Using Bismuth Trifluoride
发明人：SINGH RAJENDRA P; HU QICHAO; SHEIMAN JOHNATHAN
权利人:SES HOLDINGS PTE LTD
摘要:Methods of producing N,N-branched sulfamoyl fluoride compounds of the formula F-S(O) 2 -NR 2 by contacting bismuth trifluoride with an N,N-branched sulfamoyl nonfluorohalide compound of the formula X-SO 2 NR 2 , wherein X=chlorine (Cl), bromine (Br), or iodine (I), and each R is, independently, a linear or branched alkyl, fluoroalkyl, alkenyl, fluoroalkenyl, alkynyl, or fluoroalkynyl with 1 to 12 carbon atoms, to fluorinate the N,N-branched sulfamoyl nonfluorohalide compound. This is a non-aqueous method, the purity of product is very high, and the desired product can be isolated in quantitative yield. The N,N-branched sulfamoyl fluoride compounds so produced are useful in various applications including as electrolyte solvents and additives in electrochemical devices, such as lithium batteries and capacitors, and in biological fields, among others.

专利号:US-8268936-B2
优先权日:2005-01-04
标题:Synthesis of hybrid block copolymers and uses thereof
发明人：BREITENKAMP KURT; SILL KEVIN N
权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.

专利号:US-2006172914-A1
优先权日:2005-01-04
标题:Synthesis of hybrid block copolymers and uses thereof

专利号:US-5134146-A
优先权日:1990-05-13
标题:Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma
发明人：SHOWELL GRAHAM; LOTTI VICTOR
权利人:MERCK SHARP & DOHME
摘要:The use of compounds for formula (I): ##STR1## or a salt or prodrug thereof; wherein one of X, Y, or Z is an oxygen or sulphur atom and the other two are nitrogen atoms, and the dotted circle represents two double bonds thus forming a 1,3,4-oxadiazole, 1,2,4-oxadiazole, 1,3,4-thiadiazole or 1,2,4-thiadiazole nucleus; n R 1 represents a non-aromatic azacyclic or azabicyclic ring system selected from ##STR2## wherein the broken line represents an optional chemical bond; the substituents R 3 and R 4 may be present at any position, including the point of attachment to the oxa- or thia-diazole ring, and independently represent hydrogen, C 1-4 alkyl, halo, C 1-4 alkoxy, hydroxy or carboxy, or R 3 and R 4 together represent carbonyl; n the group R 5 represents hydrogen or C 1-4 alkyl; and n R 2 represents hydrogen, C 1-8 hydrogen, C 1-8 alkyl optionally substituted by hydroxy or fluoro, C 2-8 alkenyl, OR 7 , SR 7 , NR 7 R 8 , CN, CO 2 R 7 , CONR 7 R 8 OR NHCONHR 9 where R 9 is C 1-4 alkyl; wherein R 7 and R 8 independently represent hydrogen or saturated or unsaturated C 1-4 alkyl provided that, when R 7 and R 8 in NR 7 R 8 are both hydrogen, at least one of R 3 and R 4 is C 1-4 alkyl, n in the treatment of glaucoma, novel compounds having such use, formulations containing them and their synthesis.

专利号:US-8653223-B2
优先权日:2008-04-16
标题:Transketalized compositions, synthesis, and applications
发明人：SELIFONOV SERGEY; GOETZ ADAM EDWARD; JING FENG
权利人:SELIFONOV SERGEY; GOETZ ADAM EDWARD; JING FENG; SEGETIS INC
摘要:Ketal compounds of the structure I n nand a method of preparation of the compound from polyols and oxocarboxylates, as well as uses thereof.

专利号:EP-4200277-A1
优先权日:2020-08-21
标题 :Synthesis of n,n-branched sulfamoyl fluoride compounds using bismuth trifluoride