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CAS号67-64-1 丙酮 | CAS号463-49-0 丙二烯 | CAS号594-20-7 2,2-二氯丙烷 | CAS号74-99-7 丙炔 | CAS号187737-37-7 propene | CAS号7664-39-3 氟化氢 | CAS号1871-72-3 1-bromo-2-fluor... | CAS号353-61-7 tert-butyl fluoride | CAS号65082-47-5 Methylsulfur tr... | CAS号2310-98-7 2-氯-2-溴丙烷 | CAS号1112-05-6 1,1,1-三氯-2,2-二氟丙烷 | CAS号420-99-5 1-氯-2,2-二氟丙烷 | CAS号3175-23-3 1,2,2-trichloro... | CAS号420-97-3 1,2-二氯-2-氟丙烷 | CAS号353-50-4 氟光气 | CAS号75-90-1 三氟乙醛 | CAS号680-00-2 1,1,2,2,3,3-hex... | CAS号76-19-7 八氟丙烷 | CAS号813-75-2 1,3-difluoro-2,... | CAS号811-94-9 1,2,2-Trifluoro...📜丙炔置于氢氟酸,镍体系中,化学反应生成 2,2-二氟丙烷
参考文献:Grosse; Linn,Journal Of The American Chemical Society,1942,Vol. 64,P. 2291
标题:Grosse; Linn,Journal Of The American Chemical Society,1942,Vol. 64,P. 2291
专利信息
专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人:CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.
专利号:US-8987493-B2
优先权日:2010-05-20
标题 :Process for synthesis of silane dipeptide analogs
发明人:SIEBURTH SCOTT MCNEILL; BO YINGJIAN
权利人:SIEBURTH SCOTT MCNEILL; BO YINGJIAN; Temple University—Of the Commonwealth System of Higher Education
摘要:The invention provides a method of preparing silane dipeptide analogs, comprising the steps of treating a solution of a substituted 1,2-oxasilolane with lithium metal to form a solution of the dilithium salt of a substituted 3-hydroxypropylsilanol, and reacting the solution of the dilithium salt of the substituted 3-hydroxypropylsilanol with a substituted enamine.
专利号:US-9512250-B2
优先权日:2012-02-23
标 题 :Manganese catalyzed photopolymerization of fluorinated monomers
发明人:ASANDEI ALEXANDRU D
权利人:UNIV CONNECTICUT
摘要:The disclosure discloses initiating systems for the radical polymerization of alkenes, and especially fluorine substituted alkenes. The polymerization is catalyzed by a metal carbonyl, preferably manganese carbonyl. The polymerization is initiated directly from alkyl halides at room temperature under visible white light. The polymers also allow the synthesis of block copolymers. The process comprises polymerizing at least one alkene monomer in the presence of a halide radical initiator, carbonyl catalyst and a solvent, under reaction conditions and for a time sufficient to polymerize the at least one alkene monomer to form a polymer. The present disclosure provides a method for living polymerization of alkene monomers which provides a high level of macromolecular control over the polymerization process and which leads to uniform and controllable polymeric products. This disclosure also provides a method for activating any halide (Cl, Br, I) chain ends of such polymers for the synthesis of block copolymerizations.
专利号:US-2012083627-A1
优先权日:2010-10-01
标 题:Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent
发明人:DOLBIER JR WILLIAM R; XU WEI
权利人:DOLBIER JR WILLIAM R; XU WEI; FLUOROTECH LLC; OAKWOOD PRODUCTS INC
摘要:The invention is a method of synthesizing Arylsulfur Trifluorides, such as Fluolead, by reacting BR 2 and KF (or suitable alkali metal fluoride) in acetonitrile (or other suitable solvent). The invention also comprises using the Fluolead (or its substitutes), thus prepared, in situ as deoxofluorination reagents with a suitable aldehyde, ketone, or alcohol such as one selected from the group consisting of benzaldehyde Benzaldehyde, p-Bromobenzaldehyde, p-Tolualdehyde, Acetophenone, 2-Butanone, or Isobutyraldehyde, wherein the mixture is heated to reflux until completion. The respective products are then isolated after extraction by hexane and destruction of the sulfinyl fluoride co-product.
专利号:US-9175026-B2
优先权日:2011-03-23
标题:Synthesis of thioether containing trialkoxysilanes
发明人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K
权利人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K; UNIV CALIFORNIA
摘要:The invention relates to a radical-initiated thiol-ene or thiol-yne “clickâ€? reaction that provides a simple and efficient route to diverse trialkoxysilanes. Trialkoxysilanes made in this way are obtained in quantitative to near-quantitative yields with high purity without any or minimal purification. A wide range of functional groups is tolerated in this approach, and even complex alkenes click with the silane precursors. The modular nature of these radical-based thiol-ene or thiol-yne “clickâ€? reactions allows a wide variety of pendant groups to be coupled to silane compounds that can then be coupled to a wide variety surfaces in order to modify their material properties. Consequently, such radical initiated thiol-ene and thiol-yne reactions provide facile and efficient methods for preparing an enormous number of surface-active functional trialkoxysilanes.
专利号:US-7612106-B2
优先权日:2004-12-23
标题 :Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof
发明人:BOATMAN P DOUGLAS; SCHRADER THOMAS O; SEMPLE GRAEME; SKINNER PHILIP J; JUNG JAE-KYU
权利人:ARENA PHARM INC
摘要:The present invention relates to certain fused pyrazole derivatives of Formula (Ia), and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists for the RUP25 receptor. n nAlso provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, insulin resistance, type 2 diabetes, Syndrome-X and the like. In addition, the present invention also provides for the use of the compounds of the invention in combination with other active agents such as those belonging to the class of α-glucosidase inhibitors, aldose reductase inhibitors, biguanides, HMG-CoA reductase inhibitors, squalene synthesis inhibitors, fibrates, LDL catabolism enhancers, angiotensin converting enzyme (ACE) inhibitors, insulin secretion enhancers, DP receptor antagonists, and the like.