CAS: 402-67-5; 1-Fluoro-3-Nitrobenzene

上下游产品

CAS号99-09-2 间硝基苯胺 | CAS号99-65-0 间二硝基苯 | CAS号121-51-7 3-硝基苯磺酰氯 | CAS号611-06-3 2,4-二氯硝基苯 | CAS号586-36-7 3-nitrobenzene-... | CAS号768-35-4 3-氟苯基硼酸 | CAS号24067-17-2 4-硝基苯硼酸 | CAS号13331-27-6 3-硝基苯硼酸 | CAS号121-73-3 间氯硝基苯 | CAS号98-95-3 硝基苯 | CAS号403-19-0 2-氟-4-硝基苯酚 | CAS号1526-17-6 2-氟-6-硝基苯酚 | CAS号372-19-0 3-氟苯胺 | CAS号331-20-4 3,3'-difluorohy... | CAS号399-96-2 4-氨基-2-氟苯酚 | CAS号369-35-7 2-氟-4-硝基苯胺 | CAS号364-78-3 4-氟-2-硝基苯胺 | CAS号17809-36-8 2-氟-6-硝基苯胺 | CAS号364-53-4 3,4-二硝基氟苯 | CAS号351-28-0 3-氟乙酰苯胺

间硝基苯胺置于氟化氢吡啶,Sodium Nitrite体系中,用93%的收率获得产物间氟硝基苯
参考文献:氟化氢与碱结合,通过氨基芳烃的脱氨基氟化,轻松制备芳族氟化物
标题:氟化氢与碱结合,通过氨基芳烃的脱氨基氟化,轻松制备芳族氟化物
摘要:通过将氟化氢与碱溶液结合使用,成功地实现了包括杂芳族化合物在内的氨基芳烃的一锅式脱氨氟化,即氨基芳烃的重氮化,然后将相应的重氮离子进行原位氟脱氮,以高产率生产了氟芳烃.已发现重氮化阶段在有效生产氟代芳烃中起着最重要的作用.它受到hf溶液组成的极大影响,并通过在谨慎控制的条件下使用适量的碱(例如吡啶)来增强.光化学方法有效地促进了氟脱重氮化阶段,从而以高收率提供了具有极性取代基(如羟基,硝基等)的氟代芳烃.
DOI:10.1016/0040-4020(95)00867-8

专利信息

专利号:US-5354439-A
优先权日:1990-07-16
标 题 :Process for the synthesis of fluorinated derivatives
发明人：FORAT GERARD; GILBERT LAURENT; LANGLOIS BERNARD
权利人:RHONE POULENC CHIMIE
摘要:A process for the synthesis of fluorinated organic compounds and a reagent suitable for use in the process. The process is carried out by exchange with fluorides, while preferably agitating the reaction medium with ultrasonic sound.

专利号:US-2023295162-A1
优先权日:2020-08-06
标 题 :Synthesis of novel imipridone derivatives and their evaluation for their anticancer activity
发明人：CSÃ?MPAI ANTAL; BÃ?RÃ?NY PÉTER; CZUCZI TAMÃ?S; Kovács Imre; ADAMIS BÃ?LINT; NÉMETH ZSÓFIA; MURÃ?NYI JÓZSEF; OLÃ?HNÉ SZABÓ RITA; BOSZE SZILVIA; MEZO GÃ?BOR; KOHIDAI LÃ?SZLÓ; LAJKÓ ESZTER; TAKÃ?CS ANGÉLA; Láng Orsolya; MEZO DIÃ?NA
权利人:EOETVOES LORAND TUDOMANYEGYETEM; SEMMELWEIS EGYETEM
摘要:The present invention relates to compounds of formula (I) (I) or pharmaceutically acceptable salts, and stereoisomers thereof, including enantiomers, racemic mixtures, mixtures of enantiomers, or combinations thereof, which are applicable for use in treating cancer diseases. The present invention further relates to a pharmaceutical composition comprising the above compounds.

专利号:WO-2004058727-A1
优先权日:2002-12-20
标题 :Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity
发明人：CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA
权利人:BAYER PHARMACEUTICALS CORP; CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA
摘要:This invention relates to substituted 3,5-dihydro-4H-imidazol-4-ones compounds which are useful in the treatment of obesity and obesity-related disorders, and as weight-loss and weight-control agents. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

专利号:EP-4192467-A1
优先权日:2020-08-06
标题 :Synthesis of novel imipridone derivatives and their evaluation for their anticancer activity

专利号:CN-104356003-A
优先权日:2014-09-26
标 题 :A new method for the synthesis of aromatic fluorine-containing intermediate m-fluoroaniline

专利号:CN-116437925-A
优先权日:2020-08-06
标题 :Synthesis of novel elmidone derivatives and evaluation of anticancer activity thereof