CAS: 324-41-4; 2-Bromo-6-Fluoronaphthalene

相似化合物

343-53-3 341-41-3 315-56-0

上下游产品

CAS号7499-66-3 6-溴-2-氨基萘 | CAS号87700-58-1 6-fluoro-2-naph... | CAS号15231-91-1 6-溴-2-萘酚 | CAS号5043-01-6 6-氟-2-萘甲酸 | CAS号5043-00-5 6-氟-2-萘甲酸甲酯 | CAS号5043-01-6 6-氟-2-萘甲酸

6-Fluoro-2-Naphthoyl Chloride置于偶氮二异丁腈,三氯溴甲烷,2-Mercaptopyridine-1-Oxide Sodium Salt体系中,化学反应 0.75H,以40%的收率获得2-溴-6-氟萘
参考文献: Aryl-Pyridine Derivatives As Aldosterone Synthase Inhibitors[fr] Dérivés D'Aryl-Pyridine En Tant Qu'Inhibiteurs D'Aldostérone Synthase
标题: Aryl-Pyridine Derivatives As Aldosterone Synthase Inhibitors[fr] Dérivés D'Aryl-Pyridine En Tant Qu'Inhibiteurs D'Aldostérone Synthase
摘要:本发明提供了式(i)的化合物或其药学上可接受的盐,其中r1,R2,R3,R4,R5和n在此处定义.该发明还涉及一种制造该发明化合物的方法,以及它们的治疗用途.本发明还提供了一种药理活性剂的组合和制药组合物.

专利信息

专利号:US-9370515-B2
优先权日:2013-03-07
标题 :Mixed lineage kinase inhibitors and method of treatments
发明人：GOODFELLOW VAL S; NGUYEN THONG X; RAVULA SATHEESH B; GELBARD HARRIS A
权利人:CALIFIA BIO INC; UNIV ROCHESTER
摘要:Provided herein are imidazopyridine compounds having an inhibitory effect on mixed lineage kinases (MLKs), methods of their synthesis, and methods of their therapeutic. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and pharmaceutical compositions.