CAS: 24909-72-6; (9Z)-9-Octadecenoic Acid Anhydride

相似化合物

623-65-4 645-66-9 626-29-9

上下游产品

cis-°Ctadecenoic acid (Z)-9-°Ctadecenoyl chloride acetic anhydride isobutyl chloroformatedioleoylphosphatidylcholine cinnamyl 6-deoxy-6-oleamido-1-thio-α-D-mannopyranoside 2-°Ctadec-9'-enoylcyclohexane-1,3-dione 2-oleolylcyclohexane-1,3-dione

📜油酸置于n,N'-二环己基碳二亚胺体系中,用 二氯甲烷 用作溶剂,化学反应 2.0H,反应生成油酸酐
参考文献:环保的微波辅助方案,可制备透明质酸-脂肪酸共轭物并诱导其自组装过程.
标题:环保的微波辅助方案,可制备透明质酸-脂肪酸共轭物并诱导其自组装过程.
摘要:已经开发了一种环境可持续和节能的合成工艺来制备透明质酸基纳米级材料.其在于在无溶剂条件下进行的微波促进的多糖与天然脂肪酸的酰化酰化作用.固体试剂与mw辐射的有效相互作用说明了所获得的高收率产品.获得的化合物的自组装过程非常快地发生在mw辐射下的水性介质中,因此可以开发出用于制备纳米粒子的绿色方案.
Doi:10.1016/j.Carbpol.2016.02.001

专利信息

专利号:US-2008051323-A1
优先权日:2004-08-21
标 题 :Chloroquine drug compositions and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. n The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.

专利号:US-2007060499-A1
优先权日:2005-09-15
标 题 :Chloroquine combination drugs and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.

专利号:US-2007166281-A1
优先权日:2004-08-21
标题 :Chloroquine coupled antibodies and other proteins with methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents such as therapeutic antibodies or insulin, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the drug is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to a drug directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing the drug for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and antibody or insulin to their site of action.

专利号:US-4263216-A
优先权日:1978-10-20
标题 :Diglyceride manufacture
发明人：VOLPENHEIN ROBERT A
权利人:PROCTER & GAMBLE
摘要:Saturated triglycerides are reacted with glycerol in the presence of either a glycerolysis catalyst or a pre-formed glycerate to provide a product which is a mixture of monoglycerides, triglycerides, 1,2-diglycerides and 1,3-diglycerides. The mixture is stored in the presence of a low temperature rearrangement catalyst at a storage temperature below the melting point of the glyceride ester components of the mixture and substantially all of the mixture is converted into 1,3-diglycerides. In this way there are prepared, for example, 1-palmitoyl,3-stearoyl diglyceride, 1,3-distearoyl diglyceride and 1,3-dipalmitoyl diglyceride, which are appropriate precursors for the synthesis of confectioner's hard butters, and the like.

专利号:US-2006040879-A1
优先权日:2004-08-21
标 题:Chloroquine coupled nucleic acids and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions and methods for preparing chloroquine-coupled nucleic acid compositions. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the nucleic acid needs to be released, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to a nucleic acid directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing nucleic acids for therapeutic or other medical uses. The invention also discloses nucleic acid carrier compositions that are coupled to targeting molecules for targeting the delivery of nucleic acids to their site of action.

专利号:PL-231550-B1
优先权日:2015-12-08
标 题:Synthesis of amphiphilic polysaccharide derivative and its application