CAS: 2402-95-1; 2-Chloropyridine 1-Oxide

相似化合物

2587-00-0 20173-49-3 1851-22-5

上下游产品

CAS号109-09-1 2-氯吡啶 | CAS号14150-95-9 2-氨基吡啶 N-氧化物 | CAS号2403-02-3 2-nitro-1-oxido... | CAS号75-36-5 乙酰氯 | CAS号33252-30-1 2-氯-4-氰基吡啶 | CAS号33252-29-8 2-氯-6-氰基吡啶 | CAS号38767-72-5 4-氨基-2-羟基吡啶 | CAS号45644-21-1 2-氨基-6-氯吡啶 | CAS号4487-50-7 2-氨基-4-硝基吡啶 | CAS号4093-89-4 2-甲基氨基-5-硝基吡啶 | CAS号20773-98-2 6-methoxy-1-oxi... | CAS号6091-44-7 哌啶盐酸盐 | CAS号6313-54-8 2-氯异烟酸 | CAS号70593-61-2 6-氯吡啶-2-羧酰胺

2-氯吡啶置于双氧水体系中,用 水 用作溶剂,化学反应 7.0H,以93%的收率获得2-氯吡啶-N-氧化物
参考文献:用于h2O2氧化的可回收酸酐催化剂:吡啶衍生物的n-氧化
标题:用于h2O2氧化的可回收酸酐催化剂:吡啶衍生物的n-氧化
摘要:评估了聚(马来酸酐-Alt-1-十八碳烯)(od-Ma)和聚(马来酸酐-Alt-1-异丁烯)(bu-Ma)的催化效率和可回收性,以用于开发金属-游离的,可重复使用的催化剂,用于在 H 2 O 2存在下将吡啶氧化成吡啶n-氧化物. Od-Ma催化剂很容易通过过滤回收,回收率超过99.8%.该催化剂在多次使用后仍保持其活性,无需任何处理即可重复使用.本文所述的od-Ma和h 2 O 2催化系统环境友好,操作简单且具有成本效益.因此,它在工业上是适用的. Od-Ma 和 H 2 O 2有可能在各种氧化反应中代替过羧酸作为氧化剂.
Doi:10.1039/d0Ra00265H

专利信息

专利号:US-5886186-A
优先权日:1995-10-25
标 题 :Synthesis of substituted N-heteroaromatic compounds and methods of use thereof
发明人：SMITH ROBERT L; KUMARAVEL GNANASAMBANDAM; KUHLA DONALD E
权利人:VERSICOR INC
摘要:The subject invention features substituted N-heteroaromatic compounds, libraries of substituted N-heteroaromatic compounds, and methods of synthesis thereof. For example, the present invention provides methods for synthesizing substituted N-heteroaromatic compounds, and is particularly amenable to the generation of libraries of substituted N- heteroaromatic compounds by combinatorial chemistry. The methods of the invention generally feature the reaction of O-linked heteroaromatic N-oxides with nucleophiles to produce substituted N-heteroaromatic compounds.

专利号:US-3886180-A
优先权日:1973-03-15
标 题:Process for the synthesis of N-hydroxypyrroles
发明人：ABRAMOVITCH RUDOLPH ABRAHAM; CUE JR BERKELEY WENDELL
权利人:ABRAMOVITCH RUDOLPH ABRAHAM; CUE JR BERKELEY WENDELL
摘要:A process is described for the preparation of N-hydroxypyrrole2-carbonitriles, N-hydroxyimidazole-2-carbonitriles, pyrrole-2carbonitriles, and 3-substituted-2, 3-dihydro-2-pyrrolones by thermally decomposing 2-azidoheteroaromatic N-oxides. In the process a 2-azidoheteroaromatic N-oxide is heated in a suitable solvent for a period of time sufficient to bring the reaction to completion. Removal of the solvent by conventional methods gives the desired product. Which product is obtained is determined by the choice of solvents. In non-polar aprotic solvents, Nhydroxypyrrole-2-carbonitriles or N-hydroxyimidazole-2carbonitriles are obtained. In nucleophilic solvents capable of undergoing Michael-type additions pyrrole-2-carbonitriles, imidazole-2-carbonitriles, and 3-substituted-2,3-dihydro-2pyrrolone derivatives are obtained where a solvent molecule comprises the 3-substituent. These compounds are useful as antibaterials, e.g., against E. Coli.

专利号:US-4006160-A
优先权日:1973-03-15
标题:Process for the synthesis of N-hydroxypyrroles, N-hydroxyimidazoles, and derivatives thereof
发明人：ABRAMOVITCH RUDOLPH ABRAHAM; CUE JR BERKELEY WENDELL
权利人:UNIV ALABAMA
摘要:A process is described for the preparation of N-hydroxypyrrole-2-carbonitriles, N-hydroxyimidazole-2-carbonitriles, pyrrole-2-carbonitriles, and 3-substituted-2, 3-dihydro-2-pyrrolones by thermally decomposing 2-azidoheteroaromatic N-oxides. In the process a 2-azidoheteroaromatic N-oxide is heated in a suitable solvent for a period of time sufficient to bring the reaction to completion. Removal of the solvent by conventional methods gives the desired product. Which product is obtained is determined by the choice of solvents. In non-polar aprotic solvents, N-hydroxypyrrole-2-carbonitriles or N-hydroxyimidazole-2-carbonitriles are obtained. In nucleophilic solvents capable of undergoing Michael-type additions pyrrole-2-carbonitriles, imidazole-2-carbonitriles, and 3-substituted-2,3-dihydro-2-pyrrolone derivatives are obtained where a solvent molecule comprises the 3-substituent. These compounds are useful as anti-bacterials, e.g., against E. Coli.

专利号:US-4490532-A
优先权日:1980-07-28
标 题 :Synthesis of 2-[1-(2,5-dimethylphenyl)ethylsulfonyl]pyridine-1-oxide herbicide and intermediates therefor
发明人：HARRIS JOHN W
权利人:UNIROYAL LTD
摘要:Hydrogen chloride is passed into p-xylene and acetaldehyde to form bis-1-chloroethyl ether; the latter is converted to 2-(1-chloroethyl)-1,4-dimethylbenzene by the action of sulfuric acid and hydrogen chloride. Alkali metal hydrogen sulfide in aqueous methanol or ethanol converts the 2-(1-chloroethyl)-1,4-dimethylbenzene to alpha,2,5-trimethylbenzenemethanethiol; the sodium salt of the latter reacted with 2-chloropyridine-1-oxide yields 2-[1-(2,5-dimethylphenyl)ethylthio]pyridine-1-oxide which is then oxidized with hydrogen peroxide and alkali metal tungstate or tungstic acid to form 2-[1-(2,5-dimethylphenyl)ethylsulfonyl]pyridine-1-oxide.

专利号:CN-102898365-A
优先权日:2012-08-29
标题:A high-yield, high-quality one-pot synthesis of pyrithione urea

专利号:WO-9715557-A1
优先权日:1995-10-25
标题:Synthesis of substituted n-heteroaromatic compounds by combinatorial chemistry