CAS: 17078-28-3; 4-(Dimethylamino)Phenylacetic Acid

该化合物是一种有机化合物,其特点是芳香结构,并有矿和碳酸功能组,该化合物的特点是在副位置上有一个以二甲基氨基组物替代的苯环,以及一种乙酸酸味;由于存在可进行氢结交的碳酸箱酸组物,该物质一般是白色的脱白固体,可溶于极地溶液;二甲基氨基组物有助于其基本性,并能够影响其再活动以及与生物系统的互动;该化合物在各个领域,包括制药和有机合成业,具有作为更复杂分子的构件的潜力;其特性,如熔点,沸点和特定反应活动,可因熔点等条件和其他功能组物的存在而变化;处理和储存任何化学物质时,应参考安全数据.

结构式图片

相似化合物

50438-75-0 251643-18-2 6767-29-9

欧盟法规

ECHA物质C&L通报

上下游产品

4-aminophenylacetic acid formaldehyd methyl p-aminophenylacetate α-(p-Dimethylaminophenyl)-β-dimethylaminoacrolein methyl 1,1-dimethylethyl nitroxide lithium saltcarboxy4-(dimethylamino)phenylmethyl 1,1-dimethylethyl nitroxide lithium salt (1R,2R)-trans-cyclohexanediol mono-p-dimethylaminophenylacetate (1R,2R)-trans-cyclohexanediol bis-p-dimethylaminophenylacetate

合成工艺路线路线简述

    📜对氨基苯乙酸置于sodium Methylate体系中,用 甲醇 用作溶剂,化学反应生成4-(二甲氨基)苯乙酸
    参考文献:Tadros,W. Et Al.,Journal Fur Praktische Chemie (Leipzig 1954),1973,Vol. 315,P. 1002-1008
    标题:Tadros,W. Et Al.,Journal Fur Praktische Chemie (Leipzig 1954),1973,Vol. 315,P. 1002-1008

    海关参考信息

    专利信息


    专利号:US-9574189-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries
    发明人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
    权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
    摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

    专利号:WO-2025071365-A1
    优先权日:2023-09-27
    标 题 :Flow reactor and biological polymer synthesis system including same
    发明人:JANG MYOUNG HOON; CHOI JAE SUN; CHOI MIN HYEOK
    权利人:SP2 TX INC; BIOSENSOR LABORATORIES INC
    摘要:The present invention relates to a flow reactor and a biological polymer synthesis system including same, the system comprising: a mixing reservoir in which at least one from among an amino acid, a reagent, and an additive is mixed; a reactor into which a fluid discharged from the mixing reservoir flows; a temperature regulator disposed between the mixing reservoir and the reactor so as to regulate the temperature of the fluid flowing into the reactor; and a pump for providing driving force such that the fluid flows from the mixing reservoir to the reactor, wherein the reactor includes: a column having an inlet in through which the fluid flows and an outlet through which the fluid is discharged; and a composite solid support disposed in the column.

    专利号:US-11702652-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2009264300-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-6407103-B2
    优先权日:1998-04-21
    标 题:Indeno [1,2-c] pyrazol-4-ones and their uses
    发明人:NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
    权利人:BRISTOL MYERS SQUIBB PHARMA CO
    摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-9 and their regulatory subunits know as cyclins A-H.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

    专利号:US-2020216836-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: G M Brauer, Et Al. 4-N,N-Dialkylaminophenethanols, -Alkanoic Acids And Esters: New Accelerators For Dental Composites. J Dent Res. 1981 Jul;60(7):1343-8.
    [参考文献]: J H Lee, Et Al. Interaction Of Cells On Chargeable Functional Group Gradient Surfaces. Biomaterials. 1997 Feb;18(4):351-8.
    [参考文献]: J H Lee, Et Al. Platelet Adhesion Onto Chargeable Functional Group Gradient Surfaces. J Biomed Mater Res. 1998 May;40(2):180-6.

    合成参考文献


    摘要:Wang, M.; Li, P.; Wang, L., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 330.
    摘要:Jiang, R.; Yang, P.; You, S.-L., Science of Synthesis: Knowledge Updates, (2023) 1, 141.
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