CAS: 105279-16-1; (Z)-3-(4-Chlorobenzylidene)Isobenzofuran-1(3H)-One
- 英文名称(Z)-3-(4-Chlorobenzylidene)Isobenzofuran-1(3H)-One
- 中文名称盐酸氮卓斯汀杂质E
- IUPAC名称(Z)-3-(4-chlorobenzylidene)isobenzofuran-1(3H)-one
- 其它别名Azelastine Ep Impurity E; Azelastine Ep Impurity E (Z-Isomer); (Z)-3-(4-Chlorobenzylidene)Isobenzo; 1(3H)-Isobenzofuranone, 3-[(4-Chlorophenyl)Methylene]-, (3Z)-; Azelastine Hydrochloride Impurity E As Z-Isomer; Azelastine Hydrochloride Ep Impurity E As Z-Isomer; (Z)-3-(4-Chlorobenzylidene)Isobenzofuran-1(3H)-One; (Z)-3-(4-Chlorobenzylidene)Isobenzofuran-1(3H)-One (Azelastine Impurity)
- CAS编号105279-16-1
- MFCD编号:MFCD23115631
- EINECS号:243-862-5
- FDA UNII编号:F9B1HR45M3
- 分子式:C15H9ClO2分子量:256.69
- 产品CID: 93848
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
MSDS等安全信息
上下游产品
4-chlorophenylacetic Acid phthalic anhydride 4-chlorobenzaldehyde (3-oxo-1,3-dihydro-2-benzofuran-1-yl)(triphenyl)phosphonium bromide 4-(2-carboxyphenethyl)chlorobenzene 2‐(4-chlorophenylacetyl)benzoic acid 4-[(4-chlorophenyl)methyl]-1(2H)-phthalazinone合成工艺路线路线简述
📜3-溴苯酞置于sodium Ethanolate体系中,用 四氢呋喃,乙醇 用作溶剂,化学反应 22.0H,反应生成盐酸氮卓斯汀杂质e
参考文献:Shevchuk,M. I.; Shpak,S. T.; Tolochko,A. F.,Journal Of General Chemistry Of The Ussr,1987,Vol. 57,P. 705-709
标题:Shevchuk,M. I.; Shpak,S. T.; Tolochko,A. F.,Journal Of General Chemistry Of The Ussr,1987,Vol. 57,P. 705-709
专利信息
专利号:CN-111018818-A
优先权日:2019-12-16
标 题 :Chiral phthalide compound and synthesis method of deuterated compound thereof
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/s0960-894x(01)00387-0
摘要:del Olmo E, Armas MG, López-Pérez JL, Muñoz V, Deharo E, San Feliciano A. Leishmanicidal activity of some stilbenoids and related heterocyclic compounds. Bioorganic & Medicinal Chemistry Letters. 2001 Aug;11(16):2123–6. doi: 10.1016/s0960-894x(01)00387-0.
摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2010).
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