CAS: 96-84-4; 2-(3-Hydroxy-2,4,6-Triiodobenzyl)Butanoic Acid

上下游产品

Rac-2-(3-Methoxybenzyl)Butanoic Acid 177362-57-1

📜2-甲基丁酸置于sodium Phosphate Dibasic Dodecahydrate,N-乙酰-β-丙氨酸,Palladium Diacetate,碳酸氢钠,Silver(L) Oxide体系中,用 甲醇,二氯甲烷 作为反应溶剂,化学反应 17.17H,反应生成 碘芬酸
参考文献:Pd催化的丙酸和相关脂肪酸的β-C(sp3)-H芳基化
标题:Pd催化的丙酸和相关脂肪酸的β-C(sp3)-H芳基化
摘要:据报道,丙酸和相关的α-支链脂肪酸的β-C(sp 3)-H芳基化反应普遍采用钯催化方案.通过使用n-乙酰基-β-丙氨酸作为配体,我们的方案可提供多种芳基化产物.值得注意的是,具有挑战性的底物丙酸可以通过合成获得有用的收率,而丙酸由于其索普-英戈尔德效应而没有任何加速作用,因此可以用作底物.此外,还演示了该协议的可伸缩性和综合适用性.
DOI:10.1002/chem.201705449

专利信息

专利号:US-8420850-B2
优先权日:2010-05-14
标 题:Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers
发明人：DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE
权利人:DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE; IBERHOSPITEX SA
摘要:The invention comprises compounds which are derived from a drug or a substance with therapeutic properties, and useful as reagents for the synthesis of biostable polymers including said drug in their backbone, namely polyurethanes, polyureas or polyurea urethanes that are biocompatible and biostable. The invention also comprises the processes for preparing the compounds and the polymers, and to the use of these polymers for the manufacture of medical devices.

专利号:US-2011104052-A1
优先权日:2007-12-03
标 题 :Methods of synthesis and use of chemospheres
发明人：BARNETT BRADLEY POWERS; GESCHWIND JEFFREY
权利人:UNIV JOHNS HOPKINS
摘要:The present invention provides, in general, compositions comprising a hydrogel and an agent, for example a therapeutic agent or an imaging agent, for locoregional delivery. In certain preferred embodiments of the invention, the hydrogel compositions are detectable by Magnetic Responance and CT Scan and are used for locoregional delivery of therapeutic agents, for example chemotherapeutic agents. The invention also features polymer matrix compositions comprising nanoparticles that can be loaded after polymerization with bioactive agents, for example a diagnostic agent or therapeutic agent.

专利号:US-2012059117-A1
优先权日:2010-05-14
标 题 :Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers

专利号:WO-2011141341-A1
优先权日:2010-05-14
标题:Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers

专利号:EP-2569015-A1
优先权日:2010-05-14
标题 :Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers

专利号:CN-101812108-B
优先权日:2009-11-26
标 题 :Synthesis of Hydrocortisone Butyrate