CAS: 6554-61-6; 4,5-Dichloropyrimidine

相似化合物

1780-27-4 5750-76-5 26740-71-6

上下游产品

H-pyrimidin-4-one5-chloro-3H-pyrimidin-4-one pyrimidine-4(3H)-one 5-chloro-6-oxo-1,6-dihydropyrimidin-1-ium chloride 5-chloropyrimidin-4-amine 5-chloro-4-hydrazinopyrimidine (E)-methyl 2-[2-(6-(2-chloropyrid-3-yloxy)pyrimidin-4-yloxy)phenyl]-3-methoxypropenoate

📜4(3H)-嘧啶酮置于三氯氧磷体系中,化学反应 3.0H,反应生成 4,5-二氯嘧啶
参考文献: Benzimidazole Derivatives And Their Use As Vanilloid Receptor Ligands[fr] Derives De Benzimidazoles Et Utilisation De Ceux-Ci En Tant Que Ligands Du Recepteur Vanilloide
标题: Benzimidazole Derivatives And Their Use As Vanilloid Receptor Ligands[fr] Derives De Benzimidazoles Et Utilisation De Ceux-Ci En Tant Que Ligands Du Recepteur Vanilloide
摘要:式(i)的化合物在治疗辣椒素受体介导的疾病方面很有用,如炎症性或神经病痛以及涉及感觉神经功能的疾病,如哮喘,类风湿性关节炎,骨关节炎,炎症性肠道疾病,尿失禁,偏头痛和牛皮癣.

专利信息

专利号:WO-2021033172-A1
优先权日:2019-08-20
标题:Process for the preparation of chlorantraniliprole
发明人：V ASHWIN; PRADHAN ASHOK KUMAR; PALIMKAR SANJAY SAMBHAJIRAO; MANE AVINASH SHESHRAO; KUNHIMON SYAM KUMAR UNNIARAN
权利人:EUROFINS ADVINUS LTD
摘要:The present invention relates to two novel, efficient and one-pot methods for synthesizing chlorantraniliprole. In the first scheme, Chlorantraniliprole is prepared by a novel telescopic process starting from 3-Bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid a key raw material-A (Key RM-A). In the second scheme, starting from Key RM-A, the process steps use of a novel variant of anthranilic acid (Methyl 2-amino-5-chloro-3-methylbenzoate), to get Chlorantraniliprole. Furthermore, the present invention also relates to the synthesis of key starting material for the synthesizing chlorantraniliprole in-situ. All the in-situ steps of the disclosed synthesis methods obtain good yield, without using any expensive reagent or base or harsh reaction conditions, which makes the process simple, environment friendly and more cost effective. With this process the production cost of chlorantraniliprole and its intermediates is substantially reduced; fewer by-products are formed during its synthesis and since it's a one-pot reaction, isolation and purification are easy to achieve.

专利号:US-2023018429-A1
优先权日:2019-11-22
标 题 :Process for synthesis of (3-chloro-2-pyridyl)hydrazine
发明人：CHOCKALINGAM DEVARAJAN; DUDHAT VIPUL; KHARATKAR RAJU MAHADEV; MAO JIANHUA; VEKARIYA PANKAJKUMAR; BHATT DHARMESH BALVANTRAI
权利人:FMC CORP; FMC AGRO SINGAPORE PTE LTD
摘要:Described herein are novel methods of synthesizing (3-chloro-2-pyridyl)hydrazine. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.

专利号:WO-2024054476-A1
优先权日:2022-09-09
标题:New processes for synthesis of (3-chloro-2-pyridyl)hydrazine
发明人：BHATT DHARMESH BALVANTRAI; CHOCKALINGAM DEVARAJAN; DUDHAT VIPUL; HOFFMAN CHRISTIAN; KHARATKAR RAJU MAHADEVRAO; MAO JIANHUA
权利人:FMC CORP; FMC AGRO SINGAPORE PTE LTD
摘要:Described herein are novel methods of synthesizing pyridylhydrazines from halogenated pyridines in the presence of a phase transfer catalyst. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamides, compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.

专利号:WO-2016071243-A1
优先权日:2014-11-05
标 题:Process for preparing halogenated alkenone ethers and their use in the synthesis of anthranilamide pesticides
发明人：BENSON STEFAN; ZIERKE THOMAS; GOETZ ROLAND; WALK BERNHARD; DOMRES MONIKA
权利人:BASF SE
摘要:The present invention relates to a process for preparing a compound of formula (III) starting from the vinyl ether (IlIa) and the compound (IIIb) with a reagent (lllc) selected from the group of sulfonylhalides or sulfonylanhydrides, e.g. methanesulfonyl chloride or p-toluenesulfonyl chloride, in the presence of a base. The present invention relates also to processes comprising further preceding and/or subsequent reaction steps, leading to anthranilamide pesticides or to precursors for them.

专利号:EP-4043451-B1
优先权日:2019-10-18
标题 :Methods for the preparation of an intermediate in the synthesis of 5-bromo-2-(3-chloro-pyridin-2-yl)-2h-pyrazole-3-carboxylic acid

专利号:US-7999090-B2
优先权日:2000-07-07
标 题:Fungal cell wall synthesis gene
发明人：TSUKAHARA KAPPEI; HATA KATSURA; SAGANE KOJI; NAKAMOTO KAZUTAKA; TSUCHIYA MAMIKO; WATANABE NAOAKI; OHBA FUMINORI; TSUKADA ITARU; UEDA NORIHIRO; TANAKA KEIGO; KAI JUNKO
权利人:EISAI R&D MAN CO LTD
摘要:The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.