CAS: 652-03-9; Tetrafluorophthalic Acid

上下游产品

CAS号34973-43-8 hexachloro-phthalide | CAS号652-12-0 3,4,5,6-四氟苯酐 | CAS号1835-65-0 3,4,5,6-四氟邻苯二腈 | CAS号1024-59-5 3,4,5,6-tetrafl... | CAS号52196-63-1 2,3,4,5,7,7,8,8... | CAS号59514-37-3 perfluorobenz°C... | CAS号122180-11-4 1,1,3,3,4,5,6,7... | CAS号20687-94-9 4,5,6,7-tetrach... | CAS号59514-38-4 perfluorobenz°C... | CAS号654-87-5 2,3,5-三氟苯甲酸 | CAS号652-12-0 3,4,5,6-四氟苯酐 | CAS号1024-59-5 3,4,5,6-tetrafl... | CAS号119385-80-7 3-氨基-2,4,5-三氟苯甲酸 | CAS号13719-84-1 Benzene-1,2-dic... | CAS号13719-82-9 1,2-Bis(bromome...

3,4,5,6-四氯苯-1,2-二甲腈 以 二甲基亚砜 作为反应溶剂,化学反应生成 3,4,5,6-四氟邻苯二甲酸
参考文献:Gmelin Handbuch Der Anorganischen Chemie,Gmelin Handbook: F: Perfhalorg.9,7,Page 50-101
标题:Gmelin Handbuch Der Anorganischen Chemie,Gmelin Handbook: F: Perfhalorg.9,7,Page 50-101

专利信息

专利号:WO-8707267-A1
优先权日:1986-05-19
标 题:Method of synthesizing tetrafluorophthalonitrile
发明人：NALEWAJEK DAVID; LOCKYER GEORGE DONALD; EIBECK RICHARD ELMER; PYSZCZEK MICHAEL FRANCIS
权利人:ALLIED CORP
摘要:A process for the preparation of compounds of the general formula C6Fx(CN)y, wherein x and y are whole integers whose sum equals 6. The process is particularly useful for the synthesis of fluorinated nitriled containing at least two cyano groups (y=2). Among the preferred compounds prepared is tetrafluorophthalonitrile, a key intermediate used as a building block in the pharmaceutical industry. In the process described, tetrafluorophthalonitrile is prepared by the reaction of a chlorinated compound of general formula C6Clx(CN)y wherein x and y are whole integers whose sum equals 6. Specifically, tetrachlorophthalonitrile is reacted with potassium fluoride in an aprotic solvent to prepare tetrafluorophthalonitrile. The fluoronitrile is produced in at least 80 % yield and a minimum purity of 98.5 %. Only one additional recrystallization is required to produce a material of > 99.5 % purity. In another embodiment, the crude tetrafluorophthalonitrile is recrystallized from a hydrocarbon alkane solvent to produce a product of > 99.5 % purity which can be used directly as an intermediate. This process represents an economical means to produce tetrafluorophthalonitrile on an industrial scale.

专利号:US-6229055-B1
优先权日:1996-04-12
标题 :Synthesis of fluorinated xanthene derivatives
发明人：KLAUBERT DIETER H; GEE KYLE R
权利人:MOLECULAR PROBES INC
摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.

专利号:US-4885386-A
优先权日:1988-10-28
标题 :Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic acid
发明人：WEMPLE JAMES N; KARRICK GREGORY L; SPENCE FLOYD G
权利人:WARNER LAMBERT CO
摘要:An improved process for the preparation of 3-chloro-2,4,5-trifluorobenzoic acid is described which involves reaction of a diester of 3,4,5,6-tetrafluoro-1,2-benzenedicarboxylic acid with a substituted amine to afford 3-amino-2,4,5-trifluorobenzoic acid followed by subsequent conversion of the amio intermediate into 3-chloro-2,4,5-trifluorobenzoic acid.

专利号:CN-120005216-A
优先权日:2025-04-01
标题:Synthesis of fluorine functionalized metal organic framework and application of fluorine functionalized metal organic framework in adsorption of radioactive thorium

专利号:JP-2886908-B2
优先权日:1988-10-28
标题:Improved synthesis of 3-chloro-2,4,5-trifluorobenzoic acid

专利号:ES-2053908-T3
优先权日:1988-10-28
标题 :IMPROVED PROCESS FOR THE SYNTHESIS OF 3-CHLORO-2,4,5-TRIFLUOROBENZOIC ACID.