CAS: 606-23-5; 1H-Indene-1,3(2H)-Dione

该化合物是一种多用途有机化合物,分子式为C9H6O2,其特点是其坚固的骨结构.这种黄色晶状固体被广泛用作有机合成的关键中间体,特别是在染料,颜料和荧光材料的生产中.它具有两种碳基之间的活性甲基组的高度反应性,使得在凝聚和循环反应中能够应用多种不同的用途.1,3-Indandione表现出极好的染色性,使它在协调化学和金属离心机方面很有价值.此外,其电子接受能力有利于有机半导体和光电子材料的开发.该化合物的稳定性和定义明确的再活动特征有助于其在合成应用中的可靠性.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

2-formylindane-1,3-dione 2-bromo-indan-1,3-dione [2,2']biindenyl-1,3,1',3'-tetraone 2,2-bis-(1,3-dioxo-indan-2-yl)-acenaphthen-1-one 2,2''-benzylidene-bis-[1,2']biindenylidene-3,1',3'-trione bindone 2-benzylidene-indan-1,3-dione truxenone

合成工艺路线路线简述

    2-乙酰苯甲酸置于potassium Tert-Butylate,盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺体系中,用 二氯甲烷,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 16.08H,反应生成 1,3-茚满二酮
    参考文献:Rapid Synthesis Of Isoquinolinones By Intramolecular Coupling Of Amides And Ketones
    标题:Rapid Synthesis Of Isoquinolinones By Intramolecular Coupling Of Amides And Ketones
    摘要:通过在存在kot-Bu/dmf的情况下,酰胺和酮的分子内偶联反应,制备了非常好产率的异喹啉酮.
    DOI:10.1039/c4Ob01948B

    海关参考信息

    专利信息


    专利号:US-6159673-A
    优先权日:1996-07-17
    标 题:Oxonol compound, light-sensitive material and process for the synthesis of oxonol compound
    发明人:NISHIGAKI JUNJI; DEGUCHI YASUAKI
    权利人:FUJI PHOTO FILM CO LTD
    摘要:An oxonol compound is represented by the following formula (I): in which Z is an atomic group that forms a cyclic amide ring; each of W1 and W2 independently is an atomic group that forms an acidic nucleus ring; and M is a cation. Other oxonol compounds, a light-sensitive material containing an oxonol compound and a process for the synthesis of an oxonol compound are also disclosed.

    专利号:EP-1473330-B1
    优先权日:1996-07-17
    标题:Process for the synthesis of oxonol compound
    发明人:NISHIGAKI JUNJI; DEGUCHI YASUAKI
    权利人:FUJI PHOTO FILM CO LTD
    摘要:An oxonol compound is represented by the following formula (I): in which each of Z, W<1> and W<2> independently is an atomic group that forms a heterocyclic ring; and M is a cation. A process for the synthesis of an oxonol compound is disclosed.

    专利号:WO-2024260915-A1
    优先权日:2023-06-19
    标题:Dynamic covalent chemistry of spiropyrans for synthesis of photoswitchable photoinitiators and uses thereof
    发明人:GARMSHAUSEN YVES
    权利人:XOLO GMBH
    摘要:The present invention relates to spiropyrans and process for the manufacture of them. In particular, a method is provided to exchange the indole and salicylaldehyde part of a spiropyran in a reversible reaction. The method is used for the synthesis of dual color photoinitiators with specific substituents and substitution patterns, which result in improved dual color volumetric printing (xolography). Furthermore, a process for locally polymerizing a starting material by dual color photopolymerization is disclosed.

    专利号:WO-9915510-A1
    优先权日:1997-09-24
    标 题:Protecting and linking groups for organic synthesis
    发明人:TOTH ISTVAN; DEKANY GYULA; KELLAM BARRY
    权利人:ALCHEMIA PTY LTD; TOTH ISTVAN; DEKANY GYULA; KELLAM BARRY
    摘要:This invention relates to methods for synthesis of organic compounds, and in particular to compounds useful as protecting and linking groups for use in the synthesis of peptides, oligosaccharides, glycopeptides and glycolipids. The invention provides protecting and linking groups which are useful in both solid phase and solution synthesis, and are particularly applicable to combinatorial synthesis. In its most general aspect, the invention provides a cyclic compound of general formula (I).

    专利号:US-6765089-B1
    优先权日:1997-09-24
    标 题 :Protecting and linking groups for organic synthesis on solid supports
    发明人:TOTH ISTVAN; DEKANY GYULA; KELLAM BARRY
    权利人:ALCHEMIA PTY LTD
    摘要:This invention relates to methods for synthesis of organic compounds, and in particular to compounds useful as protecting and linking groups for use in the synthesis of peptides, oligosaccharides, glycopeptides and glycolipids. The invention provides protecting and linking groups that are useful in both solid phase and solution synthesis, and are particularly applicable to combinatorial synthesis.

    专利号:US-2003050305-A1
    优先权日:2000-05-22
    标题:Thromboxane inhibitors, compositions and methods of use
    发明人:TEJADA INIGO SAENZ DE
    摘要:The present invention describes methods for treating or preventing sexual dysfunctions in males and females, and for enhancing sexual responses in males and females by administering a therapeutically effective amount of at least one thromboxane inhibitor, and, optionally, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase, and/or at least one vasoactive agent. The male or female may preferably be diabetic. The present invention also provides novel compositions comprising at least one thromboxane inhibitor, and, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase, and, optionally, at least one therapeutic agent, such as, vasoactive agents, nonsteroidal antiinflanmmatory compounds (NSAIDs), selective cyclooxygenase-2 (COX-2) inhibitors, anticoagulants, angiotensin converting enzymes (ACE) inhibitors, angiotensin II receptor antagonists, renin inhibitors, and mixtures thereof. The present invention also provides methods for treating or preventing ischemic heart disorders, myocardial infarction, angina pectoris, stroke, migraine, cerebral hemorrhage, cardiac fatalities, transient ischaemic attacks, complications following organ transplants, coronary artery bypasses, angioplasty, endarterectomy, atherosclerosis, pulmonary embolism, bronchial asthma, bronchitis, pneumonia, circulatory shock of various organs, nephritis, graft rejection, cancerous metastases, pregnancy-induced hypertension, preeclampsia, eclampsia, thrombotic and thromboembolic disorders, intrauterine growth, gastrointestinal disorders, renal diseases and disorders, disorders resulting from elevated uric acid levels and dysmenorrhea, and for inhibiting platelet aggregation or platelet adhesion or relaxing smooth muscles.
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: A Schulman, Et Al. Diphacinone-Induced Coagulopathy In The Dog. J Am Vet Med Assoc. 1986 Feb 15;188(4):402-5.
    [参考文献]: C Y Wang, Et Al. Inhibition By Diacylmethane Derivatives Of Mutagenicity And Nucleic Acid Binding Of 2-Aminofluorene Derivatives. J Natl Cancer Inst. 1989 Nov 15;81(22):1743-7.
    [参考文献]: C Y Wang, Et Al. Inhibition By Diacylmethane Derivatives Of Mutagenicity In Salmonella Typhimurium And Trna-Binding Of Chemical Carcinogens. Mutat Res. 1991 Mar;262(3):189-93.
    [参考文献]: E Marchut, Et Al. [参考文献]: Folia Med Cracov. 1980;22(3-4):331-9.
    [参考文献]: H C Li, Et Al. The Mobility Of Troponin C And Troponin I In Muscle. J Mol Recognit. 1997 Jul-Aug;10(4):194-201.

    合成参考文献


    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2018) 3, 166.
    摘要:Ayad, T.; Pirat, J.-L.; Virieux, D., Science of Synthesis Knowledge Updates, (2022) 1, 293.
    摘要:Shaabani, A.; Sarvary, A.; Shaabani, S., Science of Synthesis: Multicomponent Reactions, (2013) 2, 103.
    摘要:Elliott, M. C.; Jones, D. H., Science of Synthesis: Multicomponent Reactions, (2013) 2, 280.
    摘要:Rodriguez, J.; Bonne, D.; Coquerel, Y.; Constantieux, T., Science of Synthesis: Multicomponent Reactions, (2013) 2, 1.
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