专利号:WO-2009003796-A1 优先权日:2007-06-29 标 题:Method for the synthesis of neral by the isomerization of isocitrals 发明人:SCHMIDT-LEITHOFF JOACHIM; JAEKEL CHRISTOPH; PACIELLO ROCCO; HEYDRICH GUNNAR; HEIDEMANN THOMAS 权利人:BASF SE; SCHMIDT-LEITHOFF JOACHIM; JAEKEL CHRISTOPH; PACIELLO ROCCO; HEYDRICH GUNNAR; HEIDEMANN THOMAS 摘要:The present invention relates to a method for the synthesis of neral and/or geranial by the isomerization of one or more isocitrals. In particular, the invention relates to a method for the synthesis of neral in pure or enriched form, starting out from a mixture of materials containing neral and geranial and one or more isocitrals.
专利号:US-7390801-B2 优先权日:1996-12-23 标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds 发明人:THORSETT EUGENE D; PLEISS MICHAEL A; LATIMER LEE H; JOHN VARGHESE; FREEDMAN STEPHEN; BRITTON THOMAS C; AUDIA JAMES A; REEL JON K; DRESSMAN BRUCE A; DROSTE JAMES J; HENRY STEVEN S; STUCKY RUSSELL D; PORTER WARREN J 权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI 摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
专利号:WO-2023277824-A2 优先权日:2021-07-01 标 题 :Diverse functionalization of hydrosilanes and programmable synthesis of multisubstituted organosilanes enabled by neutral eosin y photocatalysis
专利号:ES-2397104-T3 优先权日:2002-12-11 标 题 :Procedure and intermediate products for the synthesis of entecavir
专利号:US-4123465-A 优先权日:1975-10-16 标 题 :Chiral tertiary phosphines 发明人:VALENTINE JR DONALD H 权利人:HOFFMANN LA ROCHE 摘要:A method for the homogeneous catalytic enantioselective hydrogenation of alkyl and alkenyl substituted acrylic acids wherein these acids are selectively hydrogenated at the double bond alpha,beta to the acid function, said hydrogenations are catalyzed by rhodium complexes of chiral tertiary phosphines. This method provides a route to chiral dihydrogeranic acid and other intermediates useful in the synthesis of chiral vitamin E, citronellal, and menthol. Novel chiral tertiary phosphines are also disclosed.
专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
[参考文献]: M L Hector, Et Al. Isolation And Characterization Of Pseudomonas Aeruginosa Mutants Deficient In The Utilization Of The Terpenoid Citronellic Acid. World J Microbiol Biotechnol. 1993 Sep;9(5):562-5.
合成参考文献
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