专利号:US-10329590-B2 优先权日:2014-05-13 标 题 :Method of producing nylon 发明人:HAAS THOMAS; ECKL EVA-MARIA; BECK SIMON 权利人:EVONIK DEGUSSA GMBH 摘要:There is provided a method of producing aminohexanoic acid and/or aminohexanoic acid ester from synthesis gas, the method comprising:n A. contacting the synthesis gas with at least one bacteria capable of carrying out the Wood-Ljungdahl pathway and the ethanol-carboxylate fermentation to produce hexanoic acid; and B. contacting the hexanoic acid with a genetically modified cell to produce aminohexanoic acid and/or aminohexanoic acid ester, wherein the genetically modified cell has an increased activity, in comparison with its wild type, of alkane monooxygenase, alcohol dehydrogenase, and ω-transaminase.
专利号:US-9481660-B2 优先权日:2006-10-02 标题 :Tetra-O-substituted butane-bridge modified NDGA derivatives, their synthesis and pharmaceutical use 发明人:HELLER JONATHAN DANIEL; CHEN QINGQI; LOPEZ ROCIO ALEJANDRA; MORRIS AMANDA JEAN 权利人:HELLER JONATHAN DANIEL; CHEN QINGQI; LOPEZ ROCIO ALEJANDRA; MORRIS AMANDA JEAN; ERIMOS PHARMACEUTICALS LLC 摘要:The present invention relates to nordihydroguaiaretic acid derivative compounds, namely, butane bridge modified nordihydroguaiaretic acid (NDGA) compounds and butane bridge modified tetra-O-substituted NDGA compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, metabolic diseases, such as diabetes and hypertension, or a proliferative disease, such as diverse types of cancers.
专利号:US-6248866-B1 优先权日:1997-10-31 标 题:Hypusine reagent for peptide synthesis 发明人:BERGERON JR RAYMOND J 权利人:UNIV FLORIDA 摘要:A derivative of hypusine useful as a reagent for synthesizing peptides containing hypusine, as well as an improved method for synthesizing the same, the derivative having the formula:wherein: Q1 and Q2 may be the same or different and are amino protective groups; Q3 is an amino protective group which is orthogonal to Q1 and Q2; and Z is a hydroxy protective group.
专利号:US-8178527-B2 优先权日:2006-10-02 标 题 :Tetra-substituted NDGA derivatives via ether bonds and carbamate bonds and their synthesis and pharmaceutical use 发明人:CHEN QINGQI; LOPEZ ROCIO ALEJANDRA; HELLER JONATHAN DANIEL; MORRIS AMANDA JEAN 权利人:CHEN QINGQI; LOPEZ ROCIO ALEJANDRA; HELLER JONATHAN DANIEL; MORRIS AMANDA JEAN; ERIMOS PHARMACEUTICALS LLC 摘要:Disclosed are nordihydroguaiaretic acid derivative compounds including various end groups bonded by a carbon atom or heteroatom though a side chain bonded to the respective hydroxy residue O groups by an ether bond or a carbamate bond, pharmaceutical compositions, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, a metabolic disease, such as diabetes, a vascular disease, such as hypertension and macular degeneration, or a proliferative disease, such as diverse types of cancers.
专利号:US-9067875-B2 优先权日:2006-10-02 标 题 :Tetra-substituted NDGA derivatives via ether bonds and carbamate bonds and their synthesis and pharmaceutical use 发明人:CHEN QINGQI; LOPEZ ROCIO ALEJANDRA; HELLER JONATHAN DANIEL; MORRIS AMANDA JEAN 权利人:CHEN QINGQI; LOPEZ ROCIO ALEJANDRA; HELLER JONATHAN DANIEL; MORRIS AMANDA JEAN; ERIMOS PHARMACEUTICALS LLC 摘要:Disclosed are nordihydroguaiaretic acid derivative compounds including various end groups bonded by a carbon atom or heteroatom though a side chain bonded to the respective hydroxy residue O groups by an ether bond or a carbamate bond, pharmaceutical compositions, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, a metabolic disease, such as diabetes, a vascular disease, such as hypertension and macular degeneration, or a proliferative disease, such as diverse types of cancers.
专利号:US-9453111-B2 优先权日:2012-02-07 标 题 :Boron-modified silazanes for synthesis of SiBNC ceramics 发明人:SINGH GURPREET; BHANDAVAT ROMIL 权利人:UNIV KANSAS STATE 摘要:New methods for synthesizing boron-modified silazanes, their use as polymer-derived ceramic precursors, and polymer-derived ceramics and composites formed therefrom are disclosed. The polymeric ceramic precursors comprise a boron-modified silazane that is a room temperature liquid-phase polymer comprising a backbone having recurring monomeric repeat units comprising boron-nitrogen bonds. Nanocomposites comprising polymer-derived ceramics and carbon nanotubes are also disclosed.
参考标题:Silicon-Containing Amino Acids And Peptides. Asymmetric Synthesis Of (Trialkylsilyl)Alanines 作者:Robert D. Walkup,Derek C. Cole,Bruce R. Whittlesey |发布日期:1995.4
合成参考文献
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