专利号:US-5200341-A 优先权日:1991-10-07 标 题:Altered gene and E. coli strains and methods useful in enhanced accumulation of proteins 发明人:OBUKOWICZ MARK G 权利人:MONSANTO CO 摘要:An rpoH gene that encodes a sigma 32 protein in which cysteine instead of arginine is at amino acid residue 268 was isolated from a mutant of Escherichia coli strain W3110. The rpoH gene has thymine instead of cytosine at the nucleotide position corresponding to 802 in the wild-type rpoH gene. Purified strains of E. coli W3110 and JM101 having a mutant rpoH gene in which thymine instead of cytosine is at the nucleotide position corresponding to 802 in a wild-type rpoH gene and a method for synthesis of proteins at enhanced levels are also disclosed. The method comprises introducing an expression vehicle into an E. coli strain containing the mutant rpoH gene of this invention.
专利号:WO-2024256370-A1 优先权日:2023-06-13 标 题 :Synthesis of glufosinate using an amidase-based process 发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.
专利号:US-2025120400-A1 优先权日:2021-12-10 标题:Synthesis of glufosinate using a hydantoinase-based process 发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.
专利号:US-11919928-B2 优先权日:2016-03-16 标题 :Method for producing dihydrotentoxin 发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI 权利人:KUMIAI CHEMICAL INDUSTRY CO 摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
专利号:US-2021386068-A1 优先权日:2018-11-07 标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides 发明人:KISTER JEREMY; SATCHIVI NORBERT M 权利人:CORTEVA AGRISCIENCE LLC 摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.
专利号:US-2021352899-A1 优先权日:2018-11-07 标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides 发明人:KISTER JEREMY; SATCHIVI NORBERT M 权利人:CORTEVA AGRISCIENCE LLC 摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.
1. Muhammad M, Rasul Jan M, Shah J, Ara B. Determination of Isoproturon in Environmental Samples using the QuEChERS Extraction-Spectrofluorimetric Method. Environ Toxicol Chem. 2019 Dec;38(12):2614-2620. doi: 10.1002/etc.4589. Epub 2019 Nov 16.
合成参考文献
参考文献:10.1007/s00253-011-3451-8 摘要:Kolvenbach BA, Dobrowinski H, Fousek J, Vlcek C, Schäffer A, Gabriel FLP, Kohler HE, Corvini PFX. An unexpected gene cluster for downstream degradation of alkylphenols in Sphingomonas sp. strain TTNP3. Applied Microbiology and Biotechnology. 2011 Jul 14;93(3):1315–24. doi: 10.1007/s00253-011-3451-8. 参考文献:10.1007/s00894-011-1169-2 摘要:Singh DV, Adeppa K, Misra K. Mechanism of isoproturon resistance in Phalaris minor: in silico design, synthesis and testing of some novel herbicides for regaining sensitivity. Journal of Molecular Modeling. 2011 Jul 15;18(4):1431–45. doi: 10.1007/s00894-011-1169-2.